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  • Tracked for
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Most Cited

  • Systematic Review
  • Open Access
537 Citations
184,362 Views
15 Pages

26 December 2023

The significant advancements in applying artificial intelligence (AI) to healthcare decision-making, medical diagnosis, and other domains have simultaneously raised concerns about the fairness and bias of AI systems. This is particularly critical in...

  • Review
  • Open Access
72 Citations
15,667 Views
24 Pages

21 March 2023

Alzheimer’s Disease (AD) is becoming increasingly prevalent across the globe, and various diagnostic and detection methods have been developed in recent years. Several techniques are available, including Automatic Pipeline Methods and Machine L...

  • Review
  • Open Access
45 Citations
21,555 Views
16 Pages

30 October 2023

Blockchain offers a cutting-edge solution for storing medical data, carrying out medical transactions, and establishing trust for medical data integration and exchange in a decentralized open healthcare network setting. While blockchain in healthcare...

  • Review
  • Open Access
44 Citations
22,832 Views
26 Pages

15 December 2023

In recent years, generative transformers have become increasingly prevalent in the field of artificial intelligence, especially within the scope of natural language processing. This paper provides a comprehensive overview of these models, beginning w...

  • Review
  • Open Access
37 Citations
28,292 Views
24 Pages

Evolving Paradigms of Recombinant Protein Production in Pharmaceutical Industry: A Rigorous Review

  • Achuth Jayakrishnan,
  • Wan Rosalina Wan Rosli,
  • Ahmad Rashidi Mohd Tahir,
  • Fashli Syafiq Abd Razak,
  • Phei Er Kee,
  • Hui Suan Ng,
  • Yik-Ling Chew,
  • Siew-Keah Lee,
  • Mahenthiran Ramasamy and
  • Kai Bin Liew
  • + 1 author

31 January 2024

Many beneficial proteins have limited natural availability, which often restricts their supply and thereby reduces their potential for therapeutic or industrial usage. The advent of recombinant DNA (rDNA) technology enables the utilization of differe...

  • Article
  • Open Access
34 Citations
8,149 Views
13 Pages

The Digital Calibration Certificate (DCC) for an End-to-End Digital Quality Infrastructure for Industry 4.0

  • Siegfried Hackel,
  • Shanna Schönhals,
  • Lutz Doering,
  • Thomas Engel and
  • Reinhard Baumfalk

6 March 2023

This article depicts the role of the Digital Calibration Certificate (DCC) for an end-to-end digital quality infrastructure and as the basis for developments that are designated by the keyword “Industry 4.0”. Furthermore, it describes the...

  • Article
  • Open Access
27 Citations
2,007 Views
16 Pages

An Explainable Multi-Model Stacked Classifier Approach for Predicting Hepatitis C Drug Candidates

  • Teuku Rizky Noviandy,
  • Aga Maulana,
  • Ghifari Maulana Idroes,
  • Rivansyah Suhendra,
  • Razief Perucha Fauzie Afidh and
  • Rinaldi Idroes

6 December 2024

Hepatitis C virus (HCV) infection affects over 71 million people worldwide, leading to severe liver diseases, including cirrhosis and hepatocellular carcinoma. The virus’s high mutation rate complicates current antiviral therapies by promoting...

  • Article
  • Open Access
26 Citations
25,062 Views
22 Pages

LSTM–Transformer-Based Robust Hybrid Deep Learning Model for Financial Time Series Forecasting

  • Md R. Kabir,
  • Dipayan Bhadra,
  • Moinul Ridoy and
  • Mariofanna Milanova

10 January 2025

The inherent challenges of financial time series forecasting demand advanced modeling techniques for reliable predictions. Effective financial time series forecasting is crucial for financial risk management and the formulation of investment decision...

  • Concept Paper
  • Open Access
26 Citations
6,794 Views
16 Pages

Digital Twins in Manufacturing: A RAMI 4.0 Compliant Concept

  • Martin Lindner,
  • Lukas Bank,
  • Johannes Schilp and
  • Matthias Weigold

10 October 2023

Digital twins are among the technologies that are considered to have high potential. At the same time, there is no uniform understanding of what this technology means. Definitions are used across disciplinary boundaries, resulting in a multitude of d...

  • Review
  • Open Access
24 Citations
31,182 Views
38 Pages

Challenges and Opportunities in the Implementation of AI in Manufacturing: A Bibliometric Analysis

  • Lorena Espina-Romero,
  • Humberto Gutiérrez Hurtado,
  • Doile Ríos Parra,
  • Rafael Alberto Vilchez Pirela,
  • Rosa Talavera-Aguirre and
  • Angélica Ochoa-Díaz

3 October 2024

This study explores the evolution and impact of research on the challenges and opportunities in the implementation of artificial intelligence (AI) in manufacturing between 2019 and August 2024. By addressing the growing integration of AI technologies...

  • Article
  • Open Access
24 Citations
7,915 Views
12 Pages

2 April 2024

Audio classification using deep learning models, which is essential for applications like voice assistants and music analysis, faces challenges when deployed on edge devices due to their limited computational resources and memory. Achieving a balance...

  • Article
  • Open Access
21 Citations
3,373 Views
14 Pages

Non-Flammable Epoxy Composition Based on Epoxy Resin DER-331 and 4-(β-Carboxyethenyl)phenoxy-phenoxycyclotriphosphazenes with Increased Adhesion to Metals

  • Anastasia Konstantinova,
  • Pavel Yudaev,
  • Aleksey Shapagin,
  • Darya Panfilova,
  • Aleksandr Palamarchuk and
  • Evgeniy Chistyakov

23 May 2024

Functional cyclophosphazenes have proven to be effective modifiers of polymer materials, significantly improving their performance properties, such as adhesive characteristics, mechanical strength, thermal stability, fire resistance, etc. In this stu...

  • Review
  • Open Access
19 Citations
13,596 Views
37 Pages

9 April 2025

Microbial enzymes have revolutionised the textile industry by replacing harmful chemicals with eco-friendly alternatives, enhancing processes such as desizing, scouring, dyeing, finishing, and promoting water conservation while reducing pollution. Th...

  • Article
  • Open Access
19 Citations
6,662 Views
22 Pages

28 March 2023

This paper draws upon the United Nations 2022 data report on the achievement of Sustainable Development Goals (SDGs) across the following four dimensions: economic, social, environmental and institutional. Ward’s method was applied to obtain cl...

  • Article
  • Open Access
16 Citations
5,903 Views
27 Pages

15 February 2023

The goal of the work is to enhance existing financial market forecasting frameworks by including an additional factor–in this example, a collection of carefully chosen tweets—into a long-short repetitive neural channel. In order to produc...

  • Article
  • Open Access
13 Citations
5,386 Views
28 Pages

1 March 2023

Identity management describes a problem by providing the authorized owners with safe and simple access to information and solutions for specific identification processes. The shortcomings of the unimodal systems have been addressed by the introductio...

  • Review
  • Open Access
11 Citations
4,172 Views
19 Pages

Cooperating and Competing Digital Twins for Industrie 4.0 in Urban Planning Contexts

  • Otthein Herzog,
  • Matthias Jarke and
  • Siegfried Zhiqiang Wu

28 November 2023

Digital twins are emerging as a prime analysis, prediction, and control concepts for enabling the Industrie 4.0 vision of cyber-physical production systems (CPPSs). Today’s growing complexity and volatility cannot be handled by monolithic digit...

  • Review
  • Open Access
11 Citations
9,422 Views
21 Pages

4 February 2024

Petrochemical feedstocks are experiencing a fast growth in demand, which will further expand their market in the coming years. This is due to an increase in the demand for petrochemical-based materials that are used in households, hospitals, transpor...

  • Article
  • Open Access
11 Citations
4,871 Views
23 Pages

Application of Coffee Silverskin Cellulose/Polyacrylamide Gel Polymer Electrolytes for Rechargeable Zinc-Ion Batteries

  • Vorrada Loryuenyong,
  • Jessada Khamsawat,
  • Panuwit Danwong,
  • Achanai Buasri and
  • Prasit Pattananuwat

2 September 2024

Rechargeable zinc-ion batteries (ZIBs) have grown in popularity due to their low cost and the abundance of resources. However, there has been little research into the development of gel polymer electrolytes (GPEs) for high voltage and capacity ZIBs....

  • Article
  • Open Access
11 Citations
6,565 Views
21 Pages

2 August 2024

This study investigates the potential health risks associated with consuming mussels (Mytilus galloprovincialis Lamarck, 1819) from the Romanian Black Sea coast between 2001 and 2023. The research focuses on heavy metal (copper, cadmium, lead, nickel...

  • Review
  • Open Access
11 Citations
26,985 Views
24 Pages

Recent Developments in Luteolin-Loaded Nanoformulations for Enhanced Anti-Carcinogenic Activities: Insights from In Vitro and In Vivo Studies

  • Muhammad Redza Fahmi Mod Razif,
  • Siok Yee Chan,
  • Yik-Ling Chew,
  • Masriana Hassan,
  • Shairyzah Ahmad Hisham,
  • Shamima Abdul Rahman,
  • Chun-Wai Mai,
  • Michelle Yee Mun Teo,
  • Phei Er Kee and
  • Kai Bin Liew
  • + 2 authors

25 October 2024

With approximately 18 million people affected by cancer in 2020 globally, scientists are exploring innovative approaches to develop effective treatments for various types of cancer. Traditional chemotherapy drugs, although effective against cancer ce...

  • Article
  • Open Access
10 Citations
3,705 Views
17 Pages

T5 for Hate Speech, Augmented Data, and Ensemble

  • Tosin Adewumi,
  • Sana Sabah Sabry,
  • Nosheen Abid,
  • Foteini Liwicki and
  • Marcus Liwicki

22 September 2023

We conduct relatively extensive investigations of automatic hate speech (HS) detection using different State-of-The-Art (SoTA) baselines across 11 subtasks spanning six different datasets. Our motivation is to determine which of the recent SoTA model...

  • Article
  • Open Access
10 Citations
129,909 Views
33 Pages

On Hens, Eggs, Temperatures and CO2: Causal Links in Earth’s Atmosphere

  • Demetris Koutsoyiannis,
  • Christian Onof,
  • Zbigniew W. Kundzewicz and
  • Antonis Christofides

13 September 2023

The scientific and wider interest in the relationship between atmospheric temperature (T) and concentration of carbon dioxide ([CO2]) has been enormous. According to the commonly assumed causality link, increased [CO2] causes a rise in T. However, re...

  • Article
  • Open Access
10 Citations
3,771 Views
17 Pages

20 September 2023

Strain sensors play a pivotal role in quantifying stress and strain across diverse domains, encompassing engineering, industry, and medicine. Their applicability has recently extended into the realm of wearable electronics, enabling real-time monitor...

  • Article
  • Open Access
9 Citations
1,511 Views
43 Pages

Smart Energy Strategy for AC Microgrids to Enhance Economic Performance in Grid-Connected and Standalone Operations: A Gray Wolf Optimizer Approach

  • Sebastian Lobos-Cornejo,
  • Luis Fernando Grisales-Noreña,
  • Fabio Andrade,
  • Oscar Danilo Montoya and
  • Daniel Sanin-Villa

3 June 2025

This study proposes an optimized energy management strategy for alternating current microgrids, integrating wind generation, battery energy storage systems (BESSs), and distribution static synchronous compensators (D-STATCOMs). The objective is to mi...

  • Article
  • Open Access
9 Citations
4,283 Views
15 Pages

Development of Tannic Acid Coated Polyvinylidene Fluoride Membrane for Filtration of River Water Containing High Natural Organic Matter

  • Rosmaya Dewi,
  • Norazanita Shamsuddin,
  • Muhammad Saifullah Abu Bakar,
  • Sutarat Thongratkaew,
  • Kajornsak Faungnawakij and
  • Muhammad Roil Bilad

20 November 2023

River water can be used as a source of drinking water. However, it is vital to consider the existence of natural organic matter (NOM) and its possible influence on water quality (low turbidity, high color). The level of NOM in river water significant...

  • Article
  • Open Access
8 Citations
6,412 Views
19 Pages

Deep-Learning-Based Real-Time Visual Pollution Detection in Urban and Textile Environments

  • Md Fahim Shahoriar Titu,
  • Abdul Aziz Chowdhury,
  • S. M. Rezwanul Haque and
  • Riasat Khan

11 January 2024

The environmental physiognomy of an area can significantly diminish its aesthetic appeal, rendering it susceptible to visual pollution, the unbeaten scourge of modern urbanization. In this study, we propose using a deep learning network and a robotic...

  • Article
  • Open Access
8 Citations
4,374 Views
15 Pages

Deep Q-Network (DQN) Model for Disease Prediction Using Electronic Health Records (EHRs)

  • Nabil M. AbdelAziz,
  • Gehan A. Fouad,
  • Safa Al-Saeed and
  • Amira M. Fawzy

7 February 2025

Many efforts have proved that deep learning models are effective for disease prediction using electronic health records (EHRs). However, these models are not yet precise enough to predict diseases. Additionally, ethical concerns and the use of cluste...

  • Article
  • Open Access
8 Citations
8,623 Views
22 Pages

10 April 2025

Eye-gaze writing technology holds significant promise but faces several limitations. Existing eye-gaze-based systems often suffer from slow performance, particularly under challenging conditions such as low-light environments, user fatigue, or excess...

  • Article
  • Open Access
8 Citations
9,529 Views
15 Pages

15 August 2024

The well-known Gaussian plume model has proven to be very useful in simulating the atmospheric dispersion of air pollutants (both gaseous and particulates). Nevertheless, the nature of the model presents problems in the actual computation of concentr...

  • Article
  • Open Access
8 Citations
6,373 Views
16 Pages

The Perceptions of Generation Z University Students about Their Futures: A Qualitative Study

  • Gül Dikeç,
  • Simge Öztürk,
  • Neslihan Taşbaşı,
  • Damla Figenergül and
  • Bilal Buğrahan Güler

8 December 2023

This study explored the future-oriented perceptions of Generation Z students in a foundation university. This study was conducted using qualitative research and a phenomenological design. The study sample consisted of 11 university students over the...

  • Review
  • Open Access
8 Citations
4,475 Views
15 Pages

15 August 2023

Among different biological methods used for advanced wastewater treatment, membrane bioreactors have demonstrated superior efficiency due to their hybrid nature, combining biological and physical processes. However, their efficient operation and cont...

  • Concept Paper
  • Open Access
8 Citations
4,305 Views
17 Pages

Digital Factory Transformation from a Servitization Perspective: Fields of Action for Developing Internal Smart Services

  • Jens Neuhüttler,
  • Maximilian Feike,
  • Janika Kutz,
  • Christian Blümel and
  • Bernd Bienzeisler

16 May 2023

In recent years, a complex set of dynamic developments driven by both the economy and the emergence of digital technologies has put pressure on manufacturing companies to adapt. The concept of servitization, i.e., the shift from a product-centric to...

  • Article
  • Open Access
7 Citations
4,335 Views
14 Pages

4 February 2024

Emotion classification using physiological signals is a promising approach that is likely to become the most prevalent method. Bio-signals such as those derived from Electrocardiograms (ECGs) and the Galvanic Skin Response (GSR) are more reliable tha...

  • Review
  • Open Access
7 Citations
9,560 Views
30 Pages

Anti-Aging Potential of Bioactive Phytoconstituents Found in Edible Medicinal Plants: A Review

  • Emeka Joshua Iweala,
  • Oluwapelumi Eniola Adurosakin,
  • Ugochukwu Innocent,
  • Conrad A. Omonhinmin,
  • Omoremime Elizabeth Dania and
  • Eziuche Amadike Ugbogu

13 June 2024

Aging is a complex biological and physiological change that leads to a loss of function in all living organisms. Although the mechanism behind the aging process is still largely unknown, scientific studies have shown that oxidative stress and age-rel...

  • Review
  • Open Access
7 Citations
6,708 Views
27 Pages

A Review of the State of the Art for the Internet of Medical Things

  • Peter Matthew,
  • Sarah Mchale,
  • Xutao Deng,
  • Ghada Nakhla,
  • Marcello Trovati,
  • Nonso Nnamoko,
  • Ella Pereira,
  • Huaizhong Zhang and
  • Mohsin Raza

24 March 2025

The technological developments in the Internet of Things (IoT), data science, artificial intelligence, wearable sensors, remote monitoring, decision support systems, fog, and edge systems have transformed digital healthcare. Especially after the pand...

  • Review
  • Open Access
7 Citations
8,249 Views
16 Pages

Recent Research on Linseed Oil Use in Wood Protection—A Review

  • Dace Cirule,
  • Ingeborga Andersone,
  • Edgars Kuka and
  • Bruno Andersons

5 September 2024

Although linseed oil (LO) has been used in wood protection for centuries, research continues to develop new and more effective formulations and treatment approaches. In the future, growing interest in LO use could be expected due to its cost and envi...

  • Review
  • Open Access
7 Citations
11,074 Views
23 Pages

Cassia alata and Its Phytochemicals: A Promising Natural Strategy in Wound Recovery

  • Jing-Wen Keng,
  • Sue-Kei Lee,
  • Sze-Huey Sang,
  • Kai-Bin Liew,
  • Swee-Sen Teo,
  • Wan Mastura Shaik Mohamed Mossadeq,
  • Sek-Chuen Chow,
  • Gabriel Akyirem Akowuah,
  • Siew-Keah Lee and
  • Yik-Ling Chew
  • + 1 author

3 June 2024

Cassia alata, a traditional herb with a global presence, is renowned for its anti-inflammatory, antibacterial, and antifungal properties, making it a go-to remedy for skin ailments. While it has demonstrated wound healing capabilities in both in vitr...

  • Article
  • Open Access
7 Citations
5,694 Views
13 Pages

Depth Analysis of Anesthesia Using EEG Signals via Time Series Feature Extraction and Machine Learning

  • Raghav V. Anand,
  • Maysam F. Abbod,
  • Shou-Zen Fan and
  • Jiann-Shing Shieh

5 May 2023

The term “anesthetic depth” refers to the extent to which a general anesthetic agent sedates the central nervous system with specific strength concentration at which it is delivered. The depth level of anesthesia plays a crucial role in d...

  • Article
  • Open Access
6 Citations
2,165 Views
28 Pages

12 February 2025

The increasing requirement for distillates, accompanied by higher quantities of heavy crude oil in world production, has positioned gas oil hydrocracking as one of the most significant processes in refineries. In the petrochemical industry, hydrocrac...

  • Article
  • Open Access
6 Citations
1,652 Views
19 Pages

Earthquake Precursors Based on Rock Acoustic Emission and Deep Learning

  • Zihan Jiang,
  • Zhiwen Zhu,
  • Giuseppe Lacidogna,
  • Leandro F. Friedrich and
  • Ignacio Iturrioz

1 August 2025

China is one of the countries severely affected by earthquakes, making precise and timely identification of earthquake precursors essential for reducing casualties and property damage. A novel method is proposed that combines a rock acoustic emission...

  • Review
  • Open Access
6 Citations
7,232 Views
17 Pages

An Overview on Spheroid and Organoid Models in Applied Studies

  • Zorislava Živković and
  • Teuta Opačak-Bernardi

4 March 2025

From its inception, cell culture has been a great scientific tool for researchers in many diverse fields. The advancement from monolayer 2D cultures into three-dimensional cellular systems enabled a better experimental tool, as the 3D culture mimics...

  • Article
  • Open Access
5 Citations
3,219 Views
13 Pages

IoT-Based Framework for COVID-19 Detection Using Machine Learning Techniques

  • Ahmed Salih Al-Khaleefa,
  • Ghazwan Fouad Kadhim Al-Musawi and
  • Tahseen Jebur Saeed

23 December 2023

Current advancements in the technology of the Internet of Things (IoT) have led to the proliferation of various applications in the healthcare sector that use IoT. Recently, it has been shown that voice signal data of the respiratory system (i.e., br...

  • Review
  • Open Access
5 Citations
3,811 Views
16 Pages

Microbiota Status and Endometrial Cancer: A Narrative Review About Possible Correlations in Affected Versus Healthy Patients

  • Carmen Imma Aquino,
  • Anthony Nicosia,
  • Arianna Ligori,
  • Agnese Immacolata Volpicelli and
  • Daniela Surico

7 November 2024

(1) Background: Microbiota could be related to tumorigenesis through the persistence of an inflammatory state, also at the endometrial level. Inflammation, in fact, is involved in the promotion of genetic instability and in a favorable microenvironme...

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Sci - ISSN 2413-4155