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Cosmetics, Volume 11, Issue 2

2024 April - 34 articles

Cover Story: The aim of this double-blind, placebo-controlled, in vivo study was to determine the effect of a topically applied 0.1% PPAR ligand on the stratum corneum (SC). Here, we demonstrate via lipidomic analysis of tape strips a trend toward an increase in long-chain triacylglycerols (C50–C56) and medium- and long-chain ceramides (C42–C50) at the superficial SC. Using confocal Raman microspectroscopy, we found a significant increase in the orthorhombic organisation of lipids at the exemplary SC depth. An increase in unfolded states in the keratin results in an increased ability to bind water. The concentrations of tightly and strongly bound water increase, while weakly bound and unbound water decrease in the entire SC. Thus, the topical PPAR ligands improve the water-holding capacity and the barrier function of the SC. View this paper
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Articles (34)

  • Article
  • Open Access
5 Citations
28,600 Views
13 Pages

Impact of Hair Damage on the Penetration Profile of Coconut, Avocado, and Argan Oils into Caucasian Hair Fibers

  • Carolina Botelho Lourenço,
  • Rebeca Mantuan Gasparin,
  • Fernanda Malanconi Thomaz,
  • Gustavo Carlos da Silva,
  • Airton Abrahao Martin,
  • Ana Cláudia Paiva-Santos and
  • Priscila Gava Mazzola

The mitigation of damaged hair conditions involves the application and penetration of substances to stabilize broken bond sites, restore lipids and proteins, reinstate hydrophobicity, and recover hair mechanical properties. Vegetable oils, in general...

  • Article
  • Open Access
5 Citations
4,605 Views
11 Pages

Nanoemulsions represent a remarkable class of colloidal systems that play a pivotal role in the encapsulation, protection, and targeted delivery of active ingredients to the skin. One of the primary objectives in skincare science is to maximize the i...

  • Article
  • Open Access
6 Citations
7,033 Views
15 Pages

Potential Benefits of a Cosmetic Ingredient Combining Thermal Spring Water and Diatom Algae Extract

  • Maria Lourdes Mourelle,
  • Jordi Segura de Yebra,
  • Jordi Ayats,
  • Maria Vitale and
  • Ana López Sánchez

The development of cosmetic ingredients improving the management of skin with irritation proclivity is an actual need. However, medical recommendations in specific cases, such as sensitive skin, include the use of as few and low-reactive ingredients...

  • Communication
  • Open Access
6 Citations
14,551 Views
8 Pages

Both hyaluronic acid (HA) and calcium hydroxylapatite (CaHA) fillers have well-established indications in cosmetic medicine. Nevertheless, limited data are available on the effectiveness of combining CaHA and HA. The purpose of this report was to dem...

  • Article
  • Open Access
11 Citations
5,819 Views
25 Pages

Eco-Designing Cosmetic Products while Preserving the Sensorial-Application Properties: An Instrumental Approach toward Sustainable Formulations

  • Giovanni Tafuro,
  • Alessia Costantini,
  • Mario Piatto,
  • Silvia Lucchetti,
  • Stefano Francescato,
  • Laura Busata,
  • Giovanni Baratto and
  • Alessandra Semenzato

Driven by growing environmental concerns and regulations, cosmetic companies are seeking reliable methods to promptly assess the possibility of replacing high-impact ingredients with sustainable alternatives. In this work, we exploited rheological an...

  • Article
  • Open Access
5 Citations
8,499 Views
22 Pages

Formulation and Characterization of Non-Toxic, Antimicrobial, and Alcohol-Free Hand Sanitizer Nanoemulgel Based on Lemon Peel Extract

  • Faten Mohamed Ibrahim,
  • Eman Samy Shalaby,
  • Mohamed Azab El-Liethy,
  • Sherif Abd-Elmaksoud,
  • Reda Sayed Mohammed,
  • Said I. Shalaby,
  • Cristina V. Rodrigues,
  • Manuela Pintado and
  • El Sayed El Habbasha

Recently, hand sanitization has gained attention for preventing disease transmission. Many on-the-market convenient dermal sanitizers contain alcohol, which can be detrimental to the skin. Therefore, three nanoemulgel formulations (LN-F1, LN-F2, LN-F...

  • Article
  • Open Access
9 Citations
5,523 Views
19 Pages

Development of a Ready-to-Use Oxyresveratrol-Enriched Extract from Artocarpus lakoocha Roxb. Using Greener Solvents and Deep Eutectic Solvents for a Whitening Agent

  • Krittanon Saesue,
  • Pornnapa Thanomrak,
  • Wipawan Prompan,
  • Warakhim Punan,
  • Nantaka Khorana,
  • Wasinee Juprasert,
  • Tammanoon Rungsang,
  • Pattravee Thong-on and
  • Jukkarin Srivilai

Oxyresveratrol (ORV) is naturally found in Artocapus lakoocha Roxb. (AL), similar to resveratrol. This AL extract has demonstrated considerable importance in dietary supplements and cosmetics for its anti-tyrosinase and antioxidant properties. There...

  • Article
  • Open Access
11 Citations
5,408 Views
16 Pages

Nanoemulsions Containing Passiflora quadrangularis L. Fruit Extracts for Cosmetic Application and Skin Efficacy Study

  • Nareekan Yanasan,
  • Worrapon Wangkananon,
  • Surapol Natakankitkul and
  • Kanokwan Kiattisin

This study aimed to determine the anti-collagenase, anti-elastase, and anti-hyaluronidase activities of Passiflora quadrangularis fruit extracts (epicarp, mesocarp, endocarp, and seed), develop stable nanoemulsions, and evaluate the efficacy of the n...

  • Article
  • Open Access
2 Citations
4,385 Views
11 Pages

Permanent Makeup (PMU) Removal with Plant Origin Extracts

  • Eleni Andreou,
  • Efstathios Rallis,
  • Sophia Hatziantoniou and
  • Vasiliki Kefala

Permanent makeup (PMU) is a popular application for the correction of face and body imperfections. It can be applied over the facial area to correct the shape and color of eyebrows, to the eyelids to create permanent eyeliner shapes, and the lips to...

  • Review
  • Open Access
1 Citations
8,626 Views
12 Pages

Alopecia areata (AA) presents a challenging and unpredictable condition associated with substantial psychosocial and financial burdens. A chronic, relapsing form of non-scarring hair loss, it affects approximately 0.1–0.2% of the population wor...

  • Review
  • Open Access
9 Citations
19,009 Views
12 Pages

Dermal injections of hyaluronic acid gel for aesthetic skin rejuvenation are becoming increasingly popular nowadays. Although these products are classified as medical devices, the regulations on their administration by licensed practitioners are stil...

  • Article
  • Open Access
6,675 Views
14 Pages

Amidst a growing shift towards eco-friendly choices in personal care products, the challenge of formulating herbal shampoos with efficacy comparable to synthetic counterparts persists. This study investigates the potential of incorporating patchouli...

  • Article
  • Open Access
3 Citations
2,951 Views
20 Pages

A Sustainable Multistage Process for Immobilizing Bioactive Compounds on Layered Double Hydroxides

  • Serena Coiai,
  • Elisa Passaglia,
  • Alice Telleschi,
  • Werner Oberhauser,
  • Maria-Beatrice Coltelli and
  • Francesca Cicogna

Hybrid systems with antioxidant properties have been developed by integrating bioactive compounds derived from plant resources with layered double hydroxides (LDHs). Anion exchange has been used to substitute intercalated nitrate anions in Mg-Al LDH...

  • Review
  • Open Access
19 Citations
52,143 Views
29 Pages

Recent Advances in Microneedling-Assisted Cosmetic Applications

  • Rania Hamed,
  • Baraah Jehad Abu Nahia,
  • Ahlam Zaid Alkilani,
  • Yasmeen Al-Adhami and
  • Rana Obaidat

Microneedling, also known as percutaneous collagen induction, using microneedling devices and fabricated microneedle patches, has been widely employed in cosmetic applications for acne scar treatment, skin care, hair loss, melasma, skin rejuvenation,...

  • Case Report
  • Open Access
4 Citations
6,011 Views
10 Pages

Histological, Clinical Assessment, and Treatment of a Permanent Filler Complication in the Upper Lip: A Case Report with 16-Year Follow-Up

  • Samuel Fiuza,
  • Tiago Marques,
  • Irving Padin,
  • Maria Teresa Carvalho,
  • Nelio Veiga,
  • Juliana Campos Hasse Fernandes,
  • Gustavo Vicentis Oliveira Fernandes and
  • Patrícia Couto

There is a considerable increase in the use of substances and medical procedures aimed at changing the esthetics of the face, particularly the appearance of the lips. Permanent fillers such as polydimethylsiloxane, also called liquid silicone, are wi...

  • Review
  • Open Access
21 Citations
26,624 Views
14 Pages

Advancements in Regenerative Medicine for Aesthetic Dermatology: A Comprehensive Review and Future Trends

  • Federica Trovato,
  • Stefano Ceccarelli,
  • Simone Michelini,
  • Giordano Vespasiani,
  • Stefania Guida,
  • Hassan Ibrahim Galadari,
  • Steven Paul Nisticò,
  • Laura Colonna and
  • Giovanni Pellacani

The growing interest in maintaining a youthful appearance has encouraged an accelerated development of innovative, minimally invasive aesthetic treatments for facial rejuvenation and regeneration. The close correlation between tissue repair, regenera...

  • Review
  • Open Access
21 Citations
9,712 Views
21 Pages

A Comprehensive Review of Essential Oil–Nanotechnology Synergy for Advanced Dermocosmetic Delivery

  • Redouane Achagar,
  • Zouhair Ait-Touchente,
  • Rafika El Ati,
  • Khalid Boujdi,
  • Abderrahmane Thoume,
  • Achraf Abdou and
  • Rachid Touzani

This review investigates the convergence of nanotechnology and essential oils in advanced dermocosmetic delivery. It outlines the pivotal role of inorganic and polymeric nanoparticles, such as titanium dioxide, zinc oxide, and gold nanocarriers, in c...

  • Review
  • Open Access
1 Citations
6,568 Views
21 Pages

Photoallergy, a unique form of skin sensitization induced by specific compounds under ultraviolet irradiation, has traditionally been investigated using animals. However, the prohibition of animal testing for the assessment of cosmetic ingredients in...

  • Article
  • Open Access
4 Citations
4,785 Views
13 Pages

In Vitro Investigation of the Cytotoxic and Antiproliferative Effects of Haberlea rhodopensis Total Extract: A Comparative Study

  • Martina I. Peeva,
  • Maya G. Georgieva,
  • Aneliya A. Balacheva,
  • Atanas Pavlov and
  • Nikolay T. Tzvetkov

Haberlea rhodopensis Friv., known also as Rhodope silivryak and the Orpheus flower, is a Balkan endemic “resurrecting” plant belonging to the Gesneriaceae family. In folk medicine, the leaves of Haberlea rhodopensis Friv. were widely used...

  • Article
  • Open Access
5 Citations
6,936 Views
12 Pages

Anti-Aging Properties of Cannabis sativa Leaf Extract against UVA Irradiation

  • Kunlathida Luangpraditkun,
  • Preeyanuch Pimjuk,
  • Preeyawass Phimnuan,
  • Wisanee Wisanwattana,
  • Chothip Wisespongpand,
  • Neti Waranuch and
  • Jarupa Viyoch

Hemp extract has garnered interest as a potential cosmeceutical agent with multifunctional activities, particularly in protecting against UV-induced skin cell aberrations and restoring aged skin cells. The ethanolic extract of Cannabis sativa leaves...

  • Article
  • Open Access
2 Citations
4,458 Views
23 Pages

The peroxisome proliferator-activated receptor (PPAR) ligands modulate a variety of skin functions but are rarely used in cosmetics. The aim of this double-blind, placebo-controlled, in vivo study was to determine the effect of a topically applied 0....

  • Communication
  • Open Access
1 Citations
4,010 Views
9 Pages

Inhibitory Effect of 2-Aza-8-oxohypoxanthine on Tyrosinase Activity and Melanin Production

  • Hisae Aoshima,
  • Ruka Mizuno,
  • Yuho Iwatsu,
  • Shiori Onishi,
  • Sayuri Hyodo,
  • Rinta Ibuki,
  • Hirokazu Kawagishi and
  • Yasukazu Saitoh

A fairy chemical, 2-aza-8-oxohypoxanthine, has exhibited broad effects on skin barrier function, leading to its launch as a cosmetic ingredient. A clinical trial on a lotion containing 0.1% 2-aza-8-oxohypoxanthine demonstrated the ability of this che...

  • Review
  • Open Access
18 Citations
12,172 Views
24 Pages

What Are the Factors That Enable Thread Lifting to Last Longer?

  • Gi-Woong Hong,
  • Hyewon Hu,
  • Soo-Yeon Park,
  • Jovian Wan and
  • Kyu-Ho Yi

Thread-lifting traditionally addressed aging-related skin laxity by leveraging precise thread placement and traction. However, recent advancements, notably cog threads, expanded its application to younger patients seeking facial contour refinement. T...

  • Article
  • Open Access
18 Citations
6,546 Views
22 Pages

Olive Leaves and Citrus Peels: From Waste to Potential Resource for Cosmetic Products

  • Nicola d’Avanzo,
  • Antonia Mancuso,
  • Rosario Mare,
  • Antonio Silletta,
  • Samantha Maurotti,
  • Ortensia Ilaria Parisi,
  • Maria Chiara Cristiano and
  • Donatella Paolino

Resource depletion and food waste accumulation represent a tremendous socio-economic and environmental problem. One promising strategy involves the use of byproducts derived from food waste as ingredients for cosmetic products. The aim of this work i...

  • Article
  • Open Access
9 Citations
12,168 Views
23 Pages

Formulation and Characterization of Niacinamide and Collagen Emulsion and Its Investigation as a Potential Cosmeceutical Product

  • Elena Dănilă,
  • Durmuș Alpaslan Kaya,
  • Valentina Anuța,
  • Lăcrămioara Popa,
  • Alina Elena Coman,
  • Ciprian Chelaru,
  • Rodica Roxana Constantinescu,
  • Cristina Dinu-Pîrvu,
  • Mădălina Georgiana Albu Kaya and
  • Mihaela Violeta Ghica

Cosmeceuticals are one of the fast-growing areas of the natural personal care industry. Cosmeceuticals are cosmetic products with medicinal or drug-like benefits that can affect the biological functioning of the skin depending on the ingredients in t...

  • Article
  • Open Access
5 Citations
6,011 Views
17 Pages

Skin microbiota, and its diversity and balance, play a key role in skin health and beauty, influencing skin moisture, barrier function, and radiance. A healthy skin microbiota limits the growth of detrimental species, protecting the skin from patholo...

  • Article
  • Open Access
6 Citations
6,645 Views
17 Pages

The inhibitory effects of Pogostemon cablin essential oil (patchouli essential oil, PEO) and its primary bioactive compound, patchouli alcohol (PA), on tyrosinase and melanin were investigated in vitro and ex vivo. Treatment with PEO and PA significa...

  • Review
  • Open Access
15 Citations
11,298 Views
21 Pages

Vitamin D is a natural photoproduct that has many beneficial effects on different organs, including skin. Active forms of vitamin D and its derivatives exert biological effects on skin cells, thus maintaining skin homeostasis. In keratinocytes, they...

  • Article
  • Open Access
1 Citations
4,416 Views
13 Pages

Knowing that biomolecules, such as β-amyrin and α-amyrin, have some pharmacological effects, the aim of this study was directed towards exploring the protective effect of Tomato Peel and Seed Extract (TPSE) for its soothing function but al...

  • Article
  • Open Access
1 Citations
4,108 Views
13 Pages

Evaluation of Teneligliptin and Retagliptin on the Clearance of Melanosome by Melanophagy in B16F1 Cells

  • Seong Hyun Kim,
  • Ji-Eun Bae,
  • Na Yeon Park,
  • Joon Bum Kim,
  • Yong Hwan Kim,
  • So Hyun Kim,
  • Gyeong Seok Oh,
  • Hee Won Wang,
  • Jeong Ho Chang and
  • Dong-Hyung Cho

A specialized membrane-bound organelle, named the melanosome, is central to the storage and transport of melanin as well as melanin synthesis in melanocytes. Although previous studies have linked melanosomal degradation to autophagy, the precise mech...

  • Article
  • Open Access
7 Citations
21,783 Views
16 Pages

28 February 2024

The global packaging industry has been growing significantly, resulting in an increase in waste and emissions. Social responsibilities, regulations and targets are shifting companies’ priorities to various sustainable practices. This study comp...

  • Article
  • Open Access
2 Citations
7,645 Views
14 Pages

Interaction of Perfumes with Cytochrome P-450 19

  • Iva Drejslarová,
  • Tomáš Ječmen and
  • Petr Hodek

23 February 2024

Cytochrome P450 (CYP) enzymes play a key role in the metabolism of foreign compounds and in the biosynthesis and catabolism of endogenous substances, including hormones. The activity of these enzymes can be affected by various xenobiotics, such as po...

  • Article
  • Open Access
7,554 Views
16 Pages

A Platform for Determining Medicinal Plants with Targeted 17β-Hydroxysteroid Dehydrogenase Modulation for Possible Hair Loss Prevention

  • Suhyeon Park,
  • Neha Kaushik,
  • Geunjeong Lee,
  • Youngju Sohn,
  • Hyehyun Hong,
  • Krishna K. Shrestha,
  • Ren-Bo An,
  • Young Kum Park,
  • Ihseop Chang and
  • June-Hyun Kim

21 February 2024

Although hair loss plays a vital physiological function in present society, their impact on shaping self-esteem is undeniable. Even though there are numerous synthetic drugs available, these days, there are issues with safety, efficiency, and unclear...

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Cosmetics - ISSN 2079-9284