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23 Results Found

  • Article
  • Open Access
14 Citations
4,451 Views
27 Pages

5 November 2018

We report on the effects of magmatic hydrothermal fluids on the mineralogical and geochemical compositions of 12U and 12L Coals from the Meitian Mine in the Meitian Coalfield, southern China. The minerals in 12U Coal are predominantly chlorite, quart...

  • Article
  • Open Access
6 Citations
2,487 Views
15 Pages

Characterization and Control of Dendrobium officinale Bud Blight Disease

  • Jinzhao Zhang,
  • Haodong Sha,
  • Weiliang Chen and
  • Bizeng Mao

Dendrobium officinale is an important traditional Chinese medicine (TCM). A disease causing bud blight in D. officinale appeared in 2021 in Yueqing city, Zhejiang Province, China. In this paper, 127 isolates were obtained from 61 plants. The isolates...

  • Article
  • Open Access
12 Citations
3,531 Views
13 Pages

Macro-Nutritional Adaptive Strategies of Moose (Alces alces) Related to Population Density

  • Yingjie Ma,
  • Heng Bao,
  • Roberta Bencini,
  • David Raubenheimer,
  • Hongliang Dou,
  • Hui Liu,
  • Sirui Wang and
  • Guangshun Jiang

31 December 2019

The distribution area of moose in China has been shrinking back toward the north and northeast because of climate change and human disturbance, and the population number has been declining. Between 2011 and 2015, we studied moose at six sites in the...

  • Article
  • Open Access
12 Citations
3,279 Views
17 Pages

Coastal blue carbon storage (CBCS) plays a key role in addressing global climate change and realizing regional carbon neutrality. Although blue carbon has been studied for some years, there is little understanding of the influence of a megacity’s com...

  • Article
  • Open Access
35 Citations
3,994 Views
17 Pages

The Potential of Neoagaro-Oligosaccharides as a Treatment of Type II Diabetes in Mice

  • Fudi Lin,
  • Dongda Yang,
  • Yayan Huang,
  • Yan Zhao,
  • Jing Ye and
  • Meitian Xiao

20 September 2019

Type 2 diabetes mellitus (T2DM) accounts for more than 90% of cases of diabetes mellitus, which is harmful to human health. Herein, neoagaro-oligosaccharides (NAOs) were prepared and their potential as a treatment of T2DM was evaluated in KunMing (KM...

  • Article
  • Open Access
10 Citations
4,523 Views
12 Pages

Enhancing Pullulan Soft Capsules with a Mixture of Glycerol and Sorbitol Plasticizers: A Multi-Dimensional Study

  • Kecheng Zhou,
  • Yucheng Yang,
  • Bingde Zheng,
  • Qiqi Yu,
  • Yayan Huang,
  • Na Zhang,
  • Shriram Mourougane Rama,
  • Xueqin Zhang,
  • Jing Ye and
  • Meitian Xiao

10 May 2023

The plasticizer is crucial in the plant-based soft capsule. However, meeting the quality requirements of these capsules with a single plasticizer is challenging. To address this issue, this study first investigated the impact of a plasticizer mixture...

  • Article
  • Open Access
5 Citations
2,338 Views
14 Pages

12 April 2023

A novel, molecularly imprinted, upconversion fluorescence probe (UCNP@MIFP) for sulfonamide sensing was fabricated by Pickering emulsion polymerization using UCNP@SiO2 particles as the stabilizer and sulfamethazine/sulfamerazine as the co-templates....

  • Article
  • Open Access
3 Citations
2,882 Views
18 Pages

Drying Process of HPMC-Based Hard Capsules: Visual Experiment and Mathematical Modeling

  • Chuqi He,
  • Yucheng Yang,
  • Mi Zhang,
  • Kecheng Zhou,
  • Yayan Huang,
  • Na Zhang,
  • Jing Ye,
  • Moses Arowo,
  • Bingde Zheng and
  • Xueqin Zhang
  • + 2 authors

5 June 2023

Using plant-based polysaccharide gels to produce hard capsules is a novel application of this technology in the medicinal field, which has garnered significant attention. However, the current manufacturing technology, particularly the drying process,...

  • Article
  • Open Access
7 Citations
3,939 Views
17 Pages

Synthesis and Biological Evaluation of Analogues of Butyrolactone I as PTP1B Inhibitors

  • Bihong Hong,
  • Jianlin He,
  • Chaochun Fan,
  • Chao Tang,
  • Qingqing Le,
  • Kaikai Bai,
  • Siwen Niu and
  • Meitian Xiao

23 October 2020

In recent years, a large number of pharmacologically active compounds containing a butenolide functional group have been isolated from secondary metabolites of marine microorganisms. Butyrolactone I was found to be produced by Aspergillus terreus iso...

  • Article
  • Open Access
16 Citations
4,496 Views
13 Pages

Simple Preparation of Diverse Neoagaro-Oligosaccharides

  • Fudi Lin,
  • Jing Ye,
  • Yayan Huang,
  • Yucheng Yang and
  • Meitian Xiao

7 May 2019

A simple method for obtaining pure and well-defined oligosaccharides was established by hydrolyzing agar with β-agarase from Vibrio natriegens. The conditions for enzymolysis were optimized as follows: a temperature of 45 °C, a pH of 8.5, a...

  • Article
  • Open Access
2,032 Views
20 Pages

21 September 2023

Both intensity and phase information are needed for structure determination by macromolecular X-ray crystallography. The diffraction experiment provides intensities. Phases must be accessed indirectly by molecular replacement, or by experimental phas...

  • Article
  • Open Access
2 Citations
2,288 Views
11 Pages

Synthesis of Sulfur-Doped Magnetic Iron Oxides for Efficient Removal of Lead from Aqueous Solutions

  • Junqing Xu,
  • Meitian Pan,
  • Cong Zou,
  • Xueqiong Huang,
  • Takeshi Hagio,
  • Ryoichi Ichino,
  • Long Kong and
  • Liang Li

20 October 2023

Heavy metal pollution poses an environmental risk, and its efficient removal and facile separation from water remains a challenge. Magnetic iron oxide, an eco-friendly, relatively stable, and easy-separation material, has been regarded as one of the...

  • Article
  • Open Access
11 Citations
4,611 Views
17 Pages

Exploring the Potential of Water-Soluble Squid Ink Melanin: Stability, Free Radical Scavenging, and Cd2+ Adsorption Abilities

  • Shuji Liu,
  • Xianwei Liu,
  • Xueqin Zhang,
  • Yongchang Su,
  • Xiao’e Chen,
  • Shuilin Cai,
  • Dengyuan Liao,
  • Nan Pan,
  • Jie Su and
  • Xiaoting Chen
  • + 2 authors

30 October 2023

Squid ink melanin can be efficiently extracted from the byproduct ink sac generated during squid processing. As a natural food colorant, it possesses inherent antioxidant properties and the capability to adsorb heavy metals. This study aims to invest...

  • Article
  • Open Access
1,166 Views
24 Pages

κ/ι-Carrageenan Blends in Plant Capsules: Achieving Harmony Between Mechanical and Disintegration Properties

  • Zhenyu Liu,
  • Chuqi He,
  • Zhibin Yang,
  • Qing Zhao,
  • Yuting Dong,
  • Jing Ye,
  • Bingde Zheng,
  • Ranjith Kumar Kankala,
  • Xueqin Zhang and
  • Meitian Xiao

9 July 2025

The fast-disintegrating capsules rapidly disintegrate in various physiological environments, ensuring therapeutic efficacy. The formulation of plant-based capsules with balanced mechanical and fast disintegration characteristics continues to present...

  • Article
  • Open Access
59 Citations
5,185 Views
17 Pages

Fucoidan Isolated from Saccharina japonica Inhibits LPS-Induced Inflammation in Macrophages via Blocking NF-κB, MAPK and JAK-STAT Pathways

  • Jing Ye,
  • Donghui Chen,
  • Zhicheng Ye,
  • Yayan Huang,
  • Na Zhang,
  • Edmund M. K. Lui,
  • Changhu Xue and
  • Meitian Xiao

24 June 2020

Fucoidan has been reported to have a variety of biological activities. However, different algae species, extraction methods, harvesting seasons, and growth regions lead to the structural variation of fucoidan, which would affect the bioactivities of...

  • Article
  • Open Access
19 Citations
4,532 Views
13 Pages

Drying Behavior and Kinetics of Drying Process of Plant-Based Enteric Hard Capsules

  • Chuqi He,
  • Haodong Wang,
  • Yucheng Yang,
  • Yayan Huang,
  • Xueqin Zhang,
  • Moses Arowo,
  • Jing Ye,
  • Na Zhang and
  • Meitian Xiao

The drying process is a significant step in the manufacturing process of enteric hard capsules, which affects the physical and chemical properties of the capsules. Thus, the drying characteristics of plant-based enteric hard capsules were investigate...

  • Article
  • Open Access
24 Citations
3,626 Views
16 Pages

ACE Inhibitory Peptide from Skin Collagen Hydrolysate of Takifugu bimaculatus as Potential for Protecting HUVECs Injury

  • Shuilin Cai,
  • Nan Pan,
  • Min Xu,
  • Yongchang Su,
  • Kun Qiao,
  • Bei Chen,
  • Bingde Zheng,
  • Meitian Xiao and
  • Zhiyu Liu

24 November 2021

Angiotensin-I-converting enzyme (ACE) is a crucial enzyme or receptor that catalyzes the generation of potent vasopressor angiotensin II (Ang II). ACE inhibitory peptides from fish showed effective ACE inhibitory activity. In this study, we reported...

  • Article
  • Open Access
42 Citations
7,918 Views
13 Pages

5 January 2020

The mechanical and barrier properties of plant-based enteric polymer films were enhanced by synergistic interactions between binary gum mixtures and adding plasticizers. The results indicated that the best ratio of gellan gum (GG) and xanthan gum (XG...

  • Feature Paper
  • Article
  • Open Access
337 Citations
28,206 Views
57 Pages

SwissFEL: The Swiss X-ray Free Electron Laser

  • Christopher J. Milne,
  • Thomas Schietinger,
  • Masamitsu Aiba,
  • Arturo Alarcon,
  • Jürgen Alex,
  • Alexander Anghel,
  • Vladimir Arsov,
  • Carl Beard,
  • Paul Beaud and
  • Simona Bettoni
  • + 105 authors

14 July 2017

The SwissFEL X-ray Free Electron Laser (XFEL) facility started construction at the Paul Scherrer Institute (Villigen, Switzerland) in 2013 and will be ready to accept its first users in 2018 on the Aramis hard X-ray branch. In the following sections...

  • Article
  • Open Access
7 Citations
7,152 Views
17 Pages

The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations

  • Michelle F. Schaffer,
  • Guanya Peng,
  • Bernhard Spingler,
  • Joachim Schnabl,
  • Meitian Wang,
  • Vincent Olieric and
  • Roland K. O. Sigel

Due to the polyanionic nature of RNA, the principles of charge neutralization and electrostatic condensation require that cations help to overcome the repulsive forces in order for RNA to adopt a three-dimensional structure. A precise structural know...

  • Article
  • Open Access
2 Citations
5,599 Views
19 Pages

Reversed-Phase Medium-Pressure Liquid Chromatography Purification of Omega-3 Fatty Acid Ethyl Esters Using AQ-C18

  • Mingxin Sang,
  • Nan Pan,
  • Jingna Wu,
  • Xiaoting Chen,
  • Shuilin Cai,
  • Huan Fang,
  • Meitian Xiao,
  • Xiaoming Jiang and
  • Zhiyu Liu

19 June 2024

Omega-3 fatty acids are in high demand due to their efficacy in treating hypertriglyceridemia and preventing cardiovascular diseases. However, the growth of the industry is hampered by low purity and insufficient productivity. This study aims to deve...

  • Article
  • Open Access
562 Views
18 Pages

Exogenous Catalase Supplementation Alleviates Fusarium graminearum Mycotoxins-Induced Oxidative Stress in Weaned Piglets

  • Shujie Liang,
  • Yunfei Jiang,
  • Chong Ling,
  • Meitian Xian,
  • Hui Ye,
  • Qingyun Cao,
  • Changming Zhang,
  • Zemin Dong,
  • Weiwei Wang and
  • Jianjun Zuo

5 September 2025

The objective of this study was to investigate the impact of exogenous catalase (CAT) on antioxidant properties, as well as on hepatic and intestinal health, in piglets exposed to Fusarium graminearum mycotoxins (FGM). Forty female weaned piglets wer...

  • Article
  • Open Access
348 Views
18 Pages

Priming with Porcine Blood Polypeptide Enhances Salt Tolerance in Wheat Seedlings

  • Yong Shen,
  • Yanling Ma,
  • Yiming Yuan,
  • Meitian Dong,
  • Yanan Wang,
  • Jilong Zhou,
  • Jinpeng Yang,
  • Yang Guo,
  • Weiwei Guo and
  • Huifang Wang
  • + 2 authors

25 September 2025

Porcine blood polypeptide (PBP) has been reported to play roles in plant growth. However, its functions in alleviating salt stress in wheat remain unclear. The present study was conducted to investigate the physiological and biochemical mechanisms un...