Skip to Content

1,450 Results Found

  • Article
  • Open Access
355 Views
31 Pages

Low-Molecular-Weight Chitosan Produced by Gamma Irradiation and Hydrogen Peroxide Promotes Immune Readiness, Antioxidant Responses, and Survival in Photobacterium damselae-Challenged Asian Seabass (Lates calcarifer)

  • Thitirat Rattanawongwiboon,
  • Natthapong Paankhao,
  • Ratchanon Chumchuen,
  • Nattaset Chinnabutra and ,
  • Wasin Saisin,
  • Benchawan Kumwan,
  • Pakapon Meachasompop,
  • Yosapon Adisornprasert,
  • Pimrawee Chaemlek and
  • Anurak Uchuwittayakul
  • + 9 authors+ 4 authors

30 August 2026

Low-molecular-weight chitosan may exhibit improved dispersion and biological accessibility compared with high-molecular-weight chitosan, but direct comparisons in Asian seabass remain limited. This study evaluated dietary low-molecular-weight chitosa...

(This article belongs to the Special Issue IJMS 25th Anniversary: Updates and Progress on Bioactives and Nutraceuticals)
  • Article
  • Open Access
40 Citations
6,308 Views
12 Pages

Oxidative Stress Response of Aspergillus oryzae Induced by Hydrogen Peroxide and Menadione Sodium Bisulfite

  • Huanhuan Shao,
  • Yayi Tu,
  • Yijing Wang,
  • Chunmiao Jiang and ,
  • Long Ma,
  • Zhihong Hu,
  • Jiangfan Wang,
  • Bin Zeng and
  • Bin He
  • + 4 authors+ 0 author

Oxidative stress response protects organisms from deleterious effects of reactive oxygen species (ROS), which can damage cellular components and cause disturbance of the cellular homeostasis. Although the defensive biochemical mechanisms have been ex...

(This article belongs to the Special Issue Recent Advances in Applied Microbiology)
  • Communication
  • Open Access
23 Citations
8,278 Views
11 Pages

7 May 2013

The surface of a glassy carbon (GC) electrode was modified with reduced graphene oxide (rGO) to evaluate the electrochemical response of the modified GC electrodes to hydrogen peroxide (H2O2) and hydrazine. The electrode potential of the GC electrode...

  • Article
  • Open Access
738 Views
18 Pages

Pten-Mediated Antioxidant Response Alleviates Hydrogen Peroxide-Induced Oxidative Damage in Tilapia Muscle

  • Jianxiang Chen,
  • Pao Xu,
  • Miaomiao Xue,
  • Jiyan He and ,
  • Huaishun Shen,
  • Hongxia Li and
  • Changyou Song
  • + 2 authors+ 0 author

The mechanisms underlying hydrogen peroxide (HP)-induced oxidative stress damage in the muscle of Nile tilapia (Oreochromis niloticus) remain poorly understood. In this study, an oxidative stress model was established through 2 mM HP exposure for 4 w...

(This article belongs to the Special Issue Antioxidant Response in Aquatic Animals, 2nd Edition)
  • Article
  • Open Access
27 Citations
7,775 Views
26 Pages

Hydrogen Peroxide Response in Leaves of Poplar (Populus simonii × Populus nigra) Revealed from Physiological and Proteomic Analyses

  • Juanjuan Yu,
  • Xin Jin,
  • Xiaomei Sun,
  • Tianxiang Gao and ,
  • Xiaomei Chen,
  • Yimin She,
  • Tingbo Jiang,
  • Sixue Chen and
  • Shaojun Dai
  • + 4 authors+ 0 author

2 October 2017

Hydrogen peroxide (H2O2) is one of the most abundant reactive oxygen species (ROS), which plays dual roles as a toxic byproduct of cell metabolism and a regulatory signal molecule in plant development and stress response. Populus simonii × Populus ni...

(This article belongs to the Special Issue Selected Papers from the 6th National Plant Protein Research Congress)
  • Article
  • Open Access
52 Citations
6,797 Views
15 Pages

Responses of Microcystis Colonies of Different Sizes to Hydrogen Peroxide Stress

  • Mixue Liu,
  • Xiaoli Shi,
  • Chao Chen,
  • Li Yu and
  • Chuang Sun

27 September 2017

Microcystis blooms have become a ubiquitous phenomenon in freshwater ecosystems, and the size of Microcystis colonies varies widely throughout the year. In the present study, hydrogen peroxide (H2O2) was applied to test the effect of this algaecide o...

(This article belongs to the Special Issue Causes, Consequences and Control of Cyanobacterial Blooms in a Changing World)
  • Communication
  • Open Access
18 Citations
4,296 Views
8 Pages

Rhodotorula mucilaginosa C2.5t1 Modulates Carotenoid Content and CAR Genes Transcript Levels to Counteract the Pro-Oxidant Effect of Hydrogen Peroxide

  • Sara Landolfo,
  • Rossella Chessa,
  • Giacomo Zara,
  • Severino Zara and ,
  • Marilena Budroni and
  • Ilaria Mannazzu
  • + 1 author+ 0 author

In order to contribute to the elucidation of the biological role of carotenoids, the cellular response to hydrogen peroxide was analyzed in the red yeast R. mucilaginosa. For that, the wild strain C2.5t1, that produces β-carotene, torulene, and...

(This article belongs to the Special Issue Microbial Pigments)
  • Article
  • Open Access
41 Citations
8,473 Views
17 Pages

The Type and Source of Reactive Oxygen Species Influences the Outcome of Oxidative Stress in Cultured Cells

  • Steffi Goffart,
  • Petra Tikkanen,
  • Craig Michell,
  • Trevor Wilson and
  • Jaakko L. O. Pohjoismäki

30 April 2021

Oxidative stress can be modeled using various different experimental approaches, such as exposing the cells or organisms to oxidative chemicals. However, the actual effects of these chemicals, outside of the immediate measured effect, have attracted...

  • Review
  • Open Access
204 Citations
55,982 Views
19 Pages

Chemistry of Hydrogen Peroxide Formation and Elimination in Mammalian Cells, and Its Role in Various Pathologies

  • Celia María Curieses Andrés,
  • José Manuel Pérez de la Lastra,
  • Celia Andrés Juan,
  • Francisco J. Plou and
  • Eduardo Pérez-Lebeña

25 July 2022

Hydrogen peroxide (H2O2) is a compound involved in some mammalian reactions and processes. It modulates and signals the redox metabolism of cells by acting as a messenger together with hydrogen sulfide (H2S) and the nitric oxide radical (•NO), a...

  • Review
  • Open Access
39 Citations
6,044 Views
17 Pages

30 November 2021

Brassinosteroids (BRs) are known as the sixth type of plant hormone participating in various physiological and biochemical activities and play an irreplaceable role in plants. Small-molecule compounds (SMCs) such as nitric oxide (NO), ethylene, hydro...

(This article belongs to the Section Molecular Biology)
  • Communication
  • Open Access
4 Citations
4,329 Views
13 Pages

Excessive hydrogen peroxide causes oxidative stress in cells. The oxidation of two tyrosine residues in proteins can generate o,o′-dityrosine, a putative biomarker for protein oxidation, which plays critical roles in a variety of organisms. Thu...

(This article belongs to the Section Aberrant Oxidation of Biomolecules)
  • Article
  • Open Access
10 Citations
2,972 Views
12 Pages

Hydrogen Peroxide Activated by Biochar-Supported Sulfidated Nano Zerovalent Iron for Removal of Sulfamethazine: Response Surface Method Approach

  • Tiao Zhang,
  • Cui Hu,
  • Qian Li,
  • Chuxin Chen and ,
  • Jianhui Hu,
  • Xiaoyu Xiao,
  • Mi Li,
  • Xiaoming Zou and
  • Liangliang Huang
  • + 4 authors+ 0 author

Biochar (BC)-supported sulfide-modified nanoscale zerovalent iron (S-nZVI/BC) was prepared using the liquid-phase reduction method for the application of the removal of sulfamethazine (SMZ) from water. The reaction conditions were optimized by the Bo...

(This article belongs to the Special Issue Heavy Metals Remediation of Soil and Water)
  • Article
  • Open Access
18 Citations
4,923 Views
17 Pages

27 September 2023

Optimization of alkaline hydrogen peroxide (AHP) pretreatment and enzymatic hydrolysis of wheat straw (WS) was carried out to enhance fermentable sugar yields with the use of glucose and xylose yields from the pretreated WS as responses. In the first...

(This article belongs to the Section Industrial Fermentation)
  • Article
  • Open Access
9 Citations
4,831 Views
18 Pages

Hydrogen Peroxide and GA3 Levels Regulate the High Night Temperature Response in Pistils of Wheat (Triticum aestivum L.)

  • Purbali Mukherjee,
  • Pavithra Suriyakumar,
  • S. Vanchinathan,
  • Veda Krishnan and ,
  • Milan Kumar Lal,
  • Prakash Kumar Jha,
  • Viswanathan Chinnusamy,
  • Anjali Anand and
  • P. V. Vara Prasad
  • + 4 authors+ 0 author

31 January 2023

High night temperature (HNT) impairs crop productivity through the reproductive failure of gametes (pollen and pistil). Though female gametophyte (pistil) is an equal partner in the seed-set, the knowledge of the antioxidant system(s) and hormonal co...

(This article belongs to the Special Issue Role of Antioxidant Metabolism in Plant Stress Responses)
  • Article
  • Open Access
389 Views
13 Pages

31 August 2026

Oxidative stress disrupts skeletal muscle cell survival and proteostasis, thereby compromising animal skeletal muscle health. As an organic selenium source, selenomethionine (SeMet) participates in antioxidant defense and selenoprotein regulation. Ho...

  • Feature Paper
  • Article
  • Open Access
63 Citations
4,694 Views
15 Pages

Zinc Uptake, Photosynthetic Efficiency and Oxidative Stress in the Seagrass Cymodocea nodosa Exposed to ZnO Nanoparticles

  • Paraskevi Malea,
  • Katerina Charitonidou,
  • Ilektra Sperdouli,
  • Zoi Mylona and
  • Michael Moustakas

29 June 2019

We characterized zinc oxide nanoparticles (ZnO NPs) by dynamic light scattering (DLS) measurements, and transmission electron microscopy (TEM), while we evaluated photosystem II (PSII) responses, Zn uptake kinetics, and hydrogen peroxide (H2O2) accum...

(This article belongs to the Special Issue The Role of Metal Ions in Biology, Biochemistry and Medicine)
  • Article
  • Open Access
25 Citations
3,987 Views
22 Pages

Identifying the Pressure Points of Acute Cadmium Stress Prior to Acclimation in Arabidopsis thaliana

  • Jana Deckers,
  • Sophie Hendrix,
  • Els Prinsen,
  • Jaco Vangronsveld and
  • Ann Cuypers

28 August 2020

The toxic metal cadmium (Cd) is a major soil pollutant. Knowledge on the acute Cd-induced stress response is required to better understand the triggers and sequence of events that precede plant acclimation. Therefore, we aimed to identify the pressur...

(This article belongs to the Special Issue ROS and Abiotic Stress in Plants)
  • Review
  • Open Access
73 Citations
5,604 Views
16 Pages

17 December 2022

Metabolism and regulation of cellular polyamine levels are crucial for living cells to maintain their homeostasis and function. Polyamine oxidases (PAOs) terminally catabolize polyamines or catalyse the back-conversion reactions when spermine is conv...

  • Article
  • Open Access
51 Citations
6,081 Views
15 Pages

Improving Polyphenolic Compounds: Antioxidant Activity in Chickpea Sprouts through Elicitation with Hydrogen Peroxide

  • Liliana León-López,
  • Yudith Escobar-Zúñiga,
  • Nancy Yareli Salazar-Salas,
  • Saraid Mora Rochín and ,
  • Edith Oliva Cuevas-Rodríguez,
  • Cuauhtémoc Reyes-Moreno and
  • Jorge Milán-Carrillo
  • + 2 authors+ 0 author

2 December 2020

Elicitation appears to be a promising alternative to enhance the bioactive compound content and biological activities of legume sprouts. Multi-response optimization by response surface methodology (RSM) with desirability function (DF) was used to opt...

(This article belongs to the Special Issue Innovative Processing Technologies for Developing Functional Ingredients and Food Products with Health Benefits from Grains)
  • Article
  • Open Access
19 Citations
6,476 Views
15 Pages

Response of Potato (Solanum Tuberosum L.) Plants to Spraying by Hydrogen Peroxide

  • Ewa Szpunar-Krok,
  • Marta Jańczak-Pieniążek,
  • Karol Skrobacz,
  • Dorota Bobrecka-Jamro and
  • Maciej Balawejder

21 March 2020

The biocidal properties of hydrogen peroxide (H2O2) could be used in plant protection. However, the effects of H2O2 foliar spraying on the performance of the potato photosynthetic apparatus are still unclear. A pot experiment was conducted to investi...

(This article belongs to the Special Issue Sustainable Development of the Bioeconomy—Challenges and Dilemmas)
  • Article
  • Open Access
1 Citations
2,390 Views
23 Pages

The Influence of AQP5 on the Response to Hydrogen Peroxide in Breast Cancer Cell Lines

  • Ivan Lučić,
  • Monika Mlinarić,
  • Ana Čipak Gašparović and
  • Lidija Milković

Breast cancer is a heterogeneous disease with varying responses to therapies. While targeted treatments have advanced, conventional therapies inducing oxidative stress remain widely used. H2O2 has emerged as a therapeutic candidate due to its role in...

(This article belongs to the Special Issue New Players in the Research of Oxidative Stress and Cancer)
  • Feature Paper
  • Article
  • Open Access
7 Citations
3,516 Views
14 Pages

A New Player in Jasmonate-Mediated Stomatal Closure: The Arabidopsis thaliana Copper Amine Oxidase β

  • Ilaria Fraudentali,
  • Chiara Pedalino,
  • Paraskevi Tavladoraki,
  • Riccardo Angelini and
  • Alessandra Cona

2 December 2021

Plant defence responses to adverse environmental conditions include different stress signalling, allowing plant acclimation and survival. Among these responses one of the most common, immediate, and effective is the modulation of the stomatal apertur...

(This article belongs to the Special Issue Plant Polyamines in Plant Stress Tolerance)
  • Article
  • Open Access
34 Citations
5,896 Views
24 Pages

Respiratory Burst Oxidase Homologs RBOHD and RBOHF as Key Modulating Components of Response in Turnip Mosaic Virus—Arabidopsis thaliana (L.) Heyhn System

  • Katarzyna Otulak-Kozieł,
  • Edmund Kozieł,
  • Józef Julian Bujarski,
  • Justyna Frankowska-Łukawska and
  • Miguel Angel Torres

12 November 2020

Turnip mosaic virus (TuMV) is one of the most important plant viruses worldwide. It has a very wide host range infecting at least 318 species in over 43 families, such as Brassicaceae, Fabaceae, Asteraceae, or Chenopodiaceae from dicotyledons. Plant...

(This article belongs to the Special Issue Signal Transduction Pathways in Plants for Resistance against Plant Pathogens 2020)
  • Article
  • Open Access
8 Citations
3,026 Views
10 Pages

Design, Synthesis of Hydrogen Peroxide Response AIE Fluorescence Probes Based on Imidazo [1,2-a] Pyridine

  • Luan Tong,
  • Yulong Yang,
  • Likang Zhang,
  • Jiali Tao and ,
  • Bin Sun,
  • Cairong Song,
  • Mengchen Qi,
  • Fengqing Yang,
  • Mingxia Zhao and
  • Junbing Jiang
  • + 5 authors+ 0 author

16 February 2024

Hydrogen peroxide (H2O2), a significant member of reactive oxygen species, plays a crucial role in oxidative stress and cell signaling. Abnormal levels of H2O2 in the body can induce damage or even impair body function, leading to the development of...

(This article belongs to the Section Organic Chemistry)
  • Review
  • Open Access
305 Citations
26,717 Views
16 Pages

4 October 2018

Hydrogen peroxide (H2O2) is an important metabolite involved in most of the redox metabolism reactions and processes of the cells. H2O2 is recognized as one of the main molecules in the sensing, modulation and signaling of redox metabolism, and it is...

  • Article
  • Open Access
109 Citations
12,809 Views
19 Pages

Oxidative and Molecular Responses in Capsicum annuum L. after Hydrogen Peroxide, Salicylic Acid and Chitosan Foliar Applications

  • Laura Mejía-Teniente,
  • Flor de Dalia Durán-Flores,
  • Angela María Chapa-Oliver,
  • Irineo Torres-Pacheco and ,
  • Andrés Cruz-Hernández,
  • Mario M. González-Chavira,
  • Rosalía V. Ocampo-Velázquez and
  • Ramón G. Guevara-González
  • + 3 authors+ 0 author

15 May 2013

Hydrogen peroxide (H2O2) is an important ROS molecule (Reactive oxygen species) that serves as a signal of oxidative stress and activation of signaling cascades as a result of the early response of the plant to biotic stress. This response can also b...

(This article belongs to the Special Issue Molecular Research in Plant Secondary Metabolism)
  • Article
  • Open Access
17 Citations
4,610 Views
23 Pages

Hydrogen Peroxide Generation as an Underlying Response to High Extracellular Inorganic Phosphate (Pi) in Breast Cancer Cells

  • Marco Antonio Lacerda-Abreu,
  • Thais Russo-Abrahão,
  • Nathália Rocco-Machado,
  • Daniela Cosentino-Gomes and ,
  • Claudia Fernanda Dick,
  • Luiz Fernando Carvalho-Kelly,
  • Michelle Tanny Cunha Nascimento,
  • Thaís Cristino Rocha-Vieira and
  • José Roberto Meyer-Fernandes
  • + 4 authors+ 0 author

18 September 2021

According to the growth rate hypothesis (GRH), tumour cells have high inorganic phosphate (Pi) demands due to accelerated proliferation. Compared to healthy individuals, cancer patients present with a nearly 2.5-fold higher Pi serum concentration. In...

(This article belongs to the Special Issue Mechanisms of Phosphate Transport)
  • Article
  • Open Access
241 Views
32 Pages

13 October 2026

Processing can alter the optical, structural, spectroscopic, morphological, and thermal characteristics of lignocellulosic fibers in different ways. Five measured states of Carludovica palmata were compared: an artisan-processed reference (PJ-0), wat...

(This article belongs to the Special Issue Advances in Natural Polymers: Cellulose and Lignin)
  • Article
  • Open Access
19 Citations
3,602 Views
15 Pages

26 October 2020

Ganoderma produces lignolytic enzymes that can degrade the lignin component of plant cell walls, causing basal stem rot to oil palms. Nitrogen sources may affect plant tolerance to root pathogens while hydrogen peroxide (H2O2), salicylic acid (SA) an...

(This article belongs to the Section Plant Genetics and Genomics)
  • Article
  • Open Access
10 Citations
4,706 Views
22 Pages

13 October 2020

Methionine oxidation plays a relevant role in cell signaling. Recently, we built a database containing thousands of proteins identified as sulfoxidation targets. Using this resource, we have now developed a computational approach aimed at characteriz...

(This article belongs to the Special Issue Biological Significance of Methionine Oxidation and Reduction)
  • Article
  • Open Access
4 Citations
2,474 Views
16 Pages

Taxonomic Identification of the Arctic Strain Nocardioides Arcticus Sp. Nov. and Global Transcriptomic Analysis in Response to Hydrogen Peroxide Stress

  • Bailin Cong,
  • Hui Zhang,
  • Shuang Li,
  • Shenghao Liu and ,
  • Jing Lin,
  • Aifang Deng,
  • Wenqi Liu and
  • Yan Yang
  • + 3 authors+ 0 author

11 September 2023

Microorganisms living in polar regions rely on specialized mechanisms to adapt to extreme environments. The study of their stress adaptation mechanisms is a hot topic in international microbiology research. In this study, a bacterial strain (Arc9.136...

(This article belongs to the Section Molecular Microbiology)
  • Article
  • Open Access
486 Views
22 Pages

21 August 2026

Corn stover (CS), as a major agricultural residue in Northeast China, suffers from inefficient anaerobic digestion (AD) due to its rigid lignocellulosic structure and the generation of inhibitory phenolic compounds during pretreatment. Alkaline hydro...

(This article belongs to the Section Ecosystem, Environment and Climate Change in Agriculture)
  • Article
  • Open Access
13 Citations
3,342 Views
20 Pages

Functional Additives in a Selected European Sea Bass (Dicentrarchus labrax) Genotype: Effects on the Stress Response and Gill Antioxidant Response to Hydrogen Peroxide (H2O2) Treatment

  • Antonio Serradell,
  • Daniel Montero,
  • Genciana Terova,
  • Simona Rimoldi and ,
  • Alex Makol,
  • Félix Acosta,
  • Aline Bajek,
  • Pierrick Haffray,
  • François Allal and
  • Silvia Torrecillas
  • + 5 authors+ 0 author

11 July 2023

Functional ingredients have profiled as suitable candidates for reinforcing the fish antioxidant response and stress tolerance. In addition, selective breeding strategies have also demonstrated a correlation between fish growth performance and suscep...

(This article belongs to the Section Aquatic Animals)
  • Case Report
  • Open Access
416 Views
12 Pages

The Response of Extensive Fungal Infections of the Soles of Feet, Palms, and Nails to Low-Dose Food-Grade Hydrogen Peroxide: A Case Report

  • Seth Ayettey,
  • Albert Amoah,
  • Mary Ayettey-Adamafio,
  • Emmanuel Tagoe and ,
  • Hannah Ayettey,
  • Hector Addo,
  • Ruth Ayettey Brew,
  • Isabella Quakyi and
  • Richard Cheng
  • + 4 authors+ 0 author

Background: Due to its growing resistance to treatment, dermatophytosis remains a major global health challenge. Recent case reports of tinea unguium resolution using low-dose food-grade hydrogen peroxide (FGHP) in two patients with 25- and 52-year h...

  • Article
  • Open Access
1,327 Views
18 Pages

Hydrogen Peroxide and Vitexin in the Signaling and Defense Responses of Passiflora incarnata Under Drought Stress

  • Felipe G. Campos,
  • Gustavo R. Barzotto,
  • Isabela Melo-Figueiredo,
  • Jonas A. V. Pagassini and
  • Carmen S. F. Boaro

7 July 2025

Hydrogen peroxide (H2O2) functions as a signaling molecule that triggers physiological and biochemical adjustments that help plants cope with environmental stress. This study evaluated the effects of foliar application of 1.5 mM H2O2 on the physiolog...

(This article belongs to the Special Issue Mitigation Strategies and Tolerance of Plants to Abiotic Stresses—2nd Edition)
  • Article
  • Open Access
1 Citations
1,641 Views
20 Pages

Structure, Function and Dynamics of mCoral, a pH-Responsive Engineered Variant of the mCherry Fluorescent Protein with Improved Hydrogen Peroxide Tolerance

  • Athena Zitti,
  • Ozan Aksakal,
  • Danoo Vitsupakorn,
  • Pierre J. Rizkallah and ,
  • Halina Mikolajek,
  • James A. Platts,
  • Georgina E. Menzies and
  • D. Dafydd Jones
  • + 3 authors+ 0 author

23 December 2025

The red fluorescent protein mCherry is one of the most widely used fluorescent proteins in biology. Here, we have changed the chromophore chemistry by converting the thioether group of M66 to a thiol group through mutation to cysteine. The new varian...

(This article belongs to the Special Issue Biomolecular Structure, Function and Interactions: 2nd Edition)
  • Article
  • Open Access
2 Citations
1,724 Views
19 Pages

Stress Responses to Hydrogen Peroxide and Hydric Stress-Related Acoustic Emissions (MHAF) in Capsicum annuum L. Applied in a Single or Combined Manner

  • Pablo L. Godínez-Mendoza,
  • Amanda K. Rico-Chávez,
  • Ireri A. Carbajal-Valenzuela,
  • Luis M. Contreras-Medina and ,
  • Rosalía V. Ocampo-Velázquez,
  • Enrique Rico-García,
  • Irineo Torres-Pacheco and
  • Ramón G. Guevara-González
  • + 3 authors+ 0 author

20 August 2025

Hydrogen peroxide (H2O2) application in several plant species has been widely studied as a plant biostimulant; however, the use of acoustic emissions related to hydric stress (MHAF) in biostimulating plants has not been widely studied, including the...

(This article belongs to the Special Issue Physiological, Biochemical and Molecular Approaches to the Stress Response in Plants)
  • Article
  • Open Access
444 Views
14 Pages

Succinate Dehydrogenase Subunit D as a Redox-Responsive Mitochondrial Component Linked to Aquaporin-Associated Hydrogen Peroxide Signaling in Glioblastoma Cells

  • Kuen-Jang Tsai,
  • Kuan-Tso Chen,
  • Chin-Chuan Tsai,
  • Zi-Xuan Hong and ,
  • Li-Ying Qiu,
  • Chan-Chuan Liu,
  • Kwang-Yu Chang,
  • Pin-Yuan Chen and
  • Chia-Hung Chien
  • + 4 authors+ 0 author

5 September 2026

Glioblastoma (GBM) frequently recurs after temozolomide (TMZ) therapy and exhibits substantial redox plasticity. Our previous work showed that the effects of hydrogen peroxide (H2O2) vary with its level and between parental and TMZ-resistant GBM cell...

(This article belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
  • Article
  • Open Access
1 Citations
1,816 Views
19 Pages

Both cardiac and skeletal muscles originate from the mesoderm, although the two tissues develop from distinct primordia within the early embryo. The shared, albeit distinctive muscle phenotype of these two cell types have led many researchers to inve...

(This article belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
  • Feature Paper
  • Review
  • Open Access
45 Citations
8,930 Views
21 Pages

18 October 2020

The endoplasmic reticulum (ER) has emerged as a source of hydrogen peroxide (H2O2) and a hub for peroxide-based signaling events. Here we outline cellular sources of ER-localized peroxide, including sources within and near the ER. Focusing on three E...

(This article belongs to the Section Intracellular and Plasma Membranes)
  • Article
  • Open Access
16 Citations
3,651 Views
13 Pages

Acute Oxidative Stress Can Paradoxically Suppress Human NRF2 Protein Synthesis by Inhibiting Global Protein Translation

  • Kaitlin M. Pensabene,
  • Joseph LaMorte,
  • Amanda E. Allender,
  • Janessa Wehr and ,
  • Prabhjot Kaur,
  • Matthew Savage and
  • Aimee L. Eggler
  • + 2 authors+ 0 author

7 September 2023

The NRF2 transcription factor is a master regulator of the cellular oxidant/electrophile response and a drug target for the prevention/treatment of chronic diseases. A major mechanism of NRF2 activation is its escape from rapid degradation, and newly...

(This article belongs to the Special Issue Oxidative Stress in Various Forms and Efficient Antioxidant Pathways in Prokaryotic and Eukaryotic Cells)
  • Article
  • Open Access
15 Citations
4,635 Views
17 Pages

Synthesis of Multifunctional Polymersomes Prepared by Polymerization-Induced Self-Assembly

  • Hien Phan,
  • Robert Cavanagh,
  • Philippa Jacob,
  • Damien Destouches and ,
  • Francis Vacherot,
  • Benedetta Brugnoli,
  • Steve Howdle,
  • Vincenzo Taresco and
  • Benoit Couturaud
  • + 4 authors+ 0 author

17 July 2023

Polymersomes are an exciting modality for drug delivery due to their structural similarity to biological cells and their ability to encapsulate both hydrophilic and hydrophobic drugs. In this regard, the current work aimed to develop multifunctional...

(This article belongs to the Section Smart and Functional Polymers)
  • Article
  • Open Access
10 Citations
2,835 Views
20 Pages

Broad Spectral Response FeOOH/BiO2−x Photocatalyst with Efficient Charge Transfer for Enhanced Photo-Fenton Synergistic Catalytic Activity

  • Pengfei Wu,
  • Yufei Qin,
  • Mengyuan Gao,
  • Rui Zheng and ,
  • Yixin Zhang,
  • Xinli Li,
  • Zhaolong Liu,
  • Yingkun Zhang,
  • Zhen Cao and
  • Qingling Liu
  • + 5 authors+ 0 author

19 February 2024

In this work, to promote the separation of photogenerated carriers, prevent the catalyst from photo-corrosion, and improve the photo-Fenton synergistic degradation of organic pollutants, the coating structure of FeOOH/BiO2−x rich in oxygen vaca...

(This article belongs to the Special Issue Advanced Photocatalysts for Energy Conversion and Environmental Applications, 2nd Edition)
  • Article
  • Open Access
9 Citations
4,014 Views
12 Pages

Decomposition of Glucose-Sensitive Layer-by-Layer Films Using Hemin, DNA, and Glucose Oxidase

  • Kentaro Yoshida,
  • Yu Kashimura,
  • Toshio Kamijo,
  • Tetsuya Ono and ,
  • Takenori Dairaku,
  • Takaya Sato,
  • Yoshitomo Kashiwagi and
  • Katsuhiko Sato
  • + 3 authors+ 0 author

4 February 2020

Glucose-sensitive films were prepared through the layer-by-layer (LbL) deposition of hemin-modified poly(ethyleneimine) (H-PEI) solution and DNA solution (containing glucose oxidase (GOx)). H-PEI/DNA + GOx multilayer films were constructed using elec...

(This article belongs to the Special Issue Biomedical Polymer Materials II)
  • Article
  • Open Access
35 Citations
7,483 Views
9 Pages

Adaptive Responses to Oxidative Stress in the Filamentous Fungal Shiraia bambusicola

  • Huaxiang Deng,
  • Jiajun Chen,
  • Ruijie Gao,
  • Xiangru Liao and
  • Yujie Cai

24 August 2016

Shiraia bambusicola can retain excellent physiological activity when challenged with maximal photo-activated hypocrellin, which causes cellular oxidative stress. The protective mechanism of this fungus against oxidative stress has not yet been report...

(This article belongs to the Special Issue Biosynthesis of Natural Products)
  • Article
  • Open Access
96 Citations
11,083 Views
18 Pages

Leaf Age-Dependent Photoprotective and Antioxidative Response Mechanisms to Paraquat-Induced Oxidative Stress in Arabidopsis thaliana

  • Julietta Moustaka,
  • Georgia Tanou,
  • Ioannis-Dimosthenis Adamakis,
  • Eleftherios P. Eleftheriou and
  • Michael Moustakas

18 June 2015

Exposure of Arabidopsis thaliana young and mature leaves to the herbicide paraquat (Pq) resulted in a localized increase of hydrogen peroxide (H2O2) in the leaf veins and the neighboring mesophyll cells, but this increase was not similar in the two...

(This article belongs to the Special Issue Effects of Herbicides and Heavy Metals to the Structure and Function of Plant Cells)
  • Review
  • Open Access
804 Citations
52,955 Views
56 Pages

Plant Defense against Insect Herbivores

  • Joel Fürstenberg-Hägg,
  • Mika Zagrobelny and
  • Søren Bak

16 May 2013

Plants have been interacting with insects for several hundred million years, leading to complex defense approaches against various insect feeding strategies. Some defenses are constitutive while others are induced, although the insecticidal defense c...

(This article belongs to the Special Issue Molecular Research in Plant Secondary Metabolism)
  • Article
  • Open Access
14 Citations
5,002 Views
14 Pages

Preparation of Microparticles Capable of Glucose-Induced Insulin Release under Physiological Conditions

  • Kentaro Yoshida,
  • Kazuma Awaji,
  • Seira Shimizu,
  • Miku Iwasaki and ,
  • Yuki Oide,
  • Megumi Ito,
  • Takenori Dairaku,
  • Tetsuya Ono,
  • Yoshitomo Kashiwagi and
  • Katsuhiko Sato
  • + 5 authors+ 0 author

18 October 2018

Hydrogen peroxide (H2O2)-sensitive layer-by-layer films were prepared based on combining phenyl boronic acid (PBA)-modified poly(allylamine) (PAH) with shikimic acid (SA)-modified-PAH through boronate ester bonds. These PBA-PAH/SA-PAH multilayer film...

  • Communication
  • Open Access
4 Citations
3,869 Views
10 Pages

Preparation of Hydrogen Peroxide Sensitive Nanofilms by a Layer-by-Layer Technique

  • Kentaro Yoshida,
  • Tetsuya Ono,
  • Takenori Dairaku,
  • Yoshitomo Kashiwagi and
  • Katsuhiko Sato

15 November 2018

H2O2-sensitive nanofilms composed of DNA and hemin-appended poly(ethyleneimine) (H-PEI) were prepared by a layer-by-layer deposition of DNA and H-PEI through an electrostatic interaction. The (H-PEI/DNA)5 film was decomposed by addition of 10 mM H2O2...

  • Article
  • Open Access
6 Citations
2,219 Views
24 Pages

Characterization and Application of Synergistically Degraded Chitosan in Aquafeeds to Promote Immunity, Antioxidative Status, and Disease Resistance in Nile Tilapia (Oreochromis niloticus)

  • Thitirat Rattanawongwiboon,
  • Natthapong Paankhao,
  • Wararut Buncharoen,
  • Nantipa Pansawat and ,
  • Benchawan Kumwan,
  • Pakapon Meachasompop,
  • Phunsin Kantha,
  • Tanavan Pansiri,
  • Theeranan Tangthong and
  • Anurak Uchuwittayakul
  • + 12 authors+ 7 authors

31 July 2025

This study investigated the immunonutritional potential of high-molecular-weight (Mw~85 kDa), non-degraded chitosan (NCS) and gamma-radiation-degraded, low-molecular-weight chitosan (RCS) incorporated into aquafeeds for Nile tilapia (Oreochromis nilo...

(This article belongs to the Special Issue Polysaccharides: Synthesis, Properties and Applications)

of 29