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Diagnostics, Volume 14, Issue 11

2024 June-1 - 145 articles

Cover Story: Hyperglycemia is a well-established cardiovascular disease risk. Hyperglycemia-induced vascular dysfunction can confound the outcomes from existing chronic cardiopulmonary diseases. Addressing preventive measures with regards to maintaining normoglycemia can not only improve clinical outcomes in diabetes, but also in chronic lung diseases such as asthma, pulmonary hypertension and chronic obstructive lung disease. Indeed, future preventive approaches that are informed by phenomics and machine learning may be able to predict which patients with underlying cardiopulmonary disease would benefit the most from nutritional and exercise regimens to reduce inflammation from borderline hyperglycemia, even before a formal diagnosis of diabetes is made. View this paper
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Articles (145)

  • Article
  • Open Access
1 Citations
1,758 Views
11 Pages

IL-6 Polymorphism as a Predisposing Genetic Factor for Gestational Diabetes or Preeclampsia Development in Pregnancy with Obesity in Relation to VEGF and VEGFF Receptor Gene Expression Modalities

  • Panagiotis Halvatsiotis,
  • Theodora Tsokaki,
  • Vasileios Tsitsis,
  • Lina Palaiodimou,
  • Georgios Tsivgoulis,
  • Iraklis Tsangaris,
  • Maria Ourania Panagiotou and
  • Dimitra Houhoula

The increased prevalence of obesity worldwide has been implicated in the alarming rise of the incidence of gestational diabetes and preeclampsia, which are both considered threatening conditions for both mother and fetus. We studied gene polymorphism...

  • Article
  • Open Access
2 Citations
1,799 Views
11 Pages

Gastro-Esophageal Cancer: Can Radiomic Parameters from Baseline 18F-FDG-PET/CT Predict the Development of Distant Metastatic Disease?

  • Ricarda Hinzpeter,
  • Seyed Ali Mirshahvalad,
  • Roshini Kulanthaivelu,
  • Andres Kohan,
  • Claudia Ortega,
  • Ur Metser,
  • Amy Liu,
  • Adam Farag,
  • Elena Elimova and
  • Patrick Veit-Haibach
  • + 3 authors

We aimed to determine if clinical parameters and radiomics combined with sarcopenia status derived from baseline 18F-FDG-PET/CT could predict developing metastatic disease and overall survival (OS) in gastroesophageal cancer (GEC). Patients referred...

  • Article
  • Open Access
5 Citations
2,299 Views
18 Pages

In recent years, Convolutional Neural Network (CNN) models have demonstrated notable advancements in various domains such as image classification and Natural Language Processing (NLP). Despite their success in image classification tasks, their potent...

  • Article
  • Open Access
4 Citations
3,306 Views
11 Pages

Clinical and Hemodynamic Features of Aneurysm Rupture in Coil Embolization of Intracranial Aneurysms

  • Tomoaki Suzuki,
  • Hitoshi Hasegawa,
  • Kohei Shibuya,
  • Hidemoto Fujiwara and
  • Makoto Oishi

Intraprocedural rupture (IPR) during coil embolization (CE) of an intracranial aneurysm is a significant clinical concern that necessitates a comprehensive understanding of its clinical and hemodynamic predictors. Between January 2012 and December 20...

  • Review
  • Open Access
3 Citations
7,088 Views
16 Pages

Background: The lack of a clear answer regarding the efficacy of physiotherapy in the treatment of cubital tunnel syndrome (CuTS) has led to attempts to critically assess the scientific studies conducted to date. Materials and Methods: Two databases...

  • Brief Report
  • Open Access
1 Citations
1,796 Views
8 Pages

Hearing impairment among adults with intellectual disability (ID) is notably prevalent yet frequently underdiagnosed due, in part, to the challenges associated with traditional hearing screening methods in this population. This study explores the eff...

  • Article
  • Open Access
3 Citations
4,732 Views
15 Pages

Management and Rehabilitative Treatment in Osteoarthritis with a Novel Physical Therapy Approach: A Randomized Control Study

  • Teresa Paolucci,
  • Marco Tommasi,
  • Giannantonio Pozzato,
  • Alessandro Pozzato,
  • Letizia Pezzi,
  • Mariachiara Zuccarini,
  • Alessio Di Lanzo,
  • Rocco Palumbo,
  • Daniele Porto and
  • Antonia Patruno
  • + 4 authors

Knee osteoarthritis (KOA) is a chronic degenerative disease characterized by progressive joint damage leading to significant disability. Although rehabilitative treatment methods for KOA have been widely implemented, the optimal integrated instrument...

  • Article
  • Open Access
5 Citations
4,059 Views
11 Pages

Purpose: The purpose of this study is to improve the qualitative and quantitative image quality of the time-resolved angiography with interleaved stochastic trajectories technique (4D-TWIST-MRA) using deep neural network (DNN)-based MR image reconstr...

  • Article
  • Open Access
1,629 Views
8 Pages

Maternal Reassurance, Satisfaction, and Anxiety after First-Trimester Screening for Aneuploidies: Comparison between Contingent Screening and Universal Cell-Free DNA Testing

  • Anna Luna Tramontano,
  • Ilaria Marano,
  • Giuliana Orlandi,
  • Antonio Angelino,
  • Maria Rivieccio,
  • Caterina Fulgione,
  • Giuseppe Maria Maruotti,
  • Gabriele Saccone,
  • Gabriella De Vita and
  • Laura Sarno
  • + 1 author

Background: This study aims to evaluate maternal reassurance, satisfaction, and anxiety after two different strategies for the first-trimester screening for aneuploidies. Methods: Patients between 11 + 3 and 13 + 6 weeks of gestation attending the fi...

  • Article
  • Open Access
2 Citations
2,096 Views
11 Pages

Myocardial Work Indices Predict Hospitalization in Patients with Advanced Heart Failure

  • Giulia Elena Mandoli,
  • Federico Landra,
  • Benedetta Chiantini,
  • Lorenzo Bonadiman,
  • Maria Concetta Pastore,
  • Marta Focardi,
  • Flavio D’Ascenzi,
  • Matteo Lisi,
  • Enrico Emilio Diviggiano and
  • Michael Y. Henein
  • + 5 authors

Background: An increasing proportion of heart failure (HF) patients progress to the advanced stage (AdHF) with high event rates and limited treatment options. Echocardiography, particularly Speckle Tracking-derived myocardial work (MW), is useful for...

  • Article
  • Open Access
2 Citations
1,574 Views
8 Pages

Dynamic Perviousness: A Novel Imaging Marker for Predicting Mechanical Thrombectomy Outcomes in Acute Ischemic Stroke

  • Daniel F. Toth,
  • Gergely Bertalan,
  • Priska Heinz,
  • Jawid Madjidyar,
  • Patrick Thurner,
  • Tilman Schubert and
  • Zsolt Kulcsar

Background: The predictive value of thrombus standard perviousness (SP) in acute ischemic stroke (AIS) for the technical success rates of mechanical thrombectomy (MT) or functional outcomes is not yet conclusive. We investigated the relationship betw...

  • Article
  • Open Access
2,179 Views
11 Pages

CXCR4 Expression as a Prognostic Biomarker in Soft Tissue Sarcomas

  • Anna C. Virgili,
  • Juliana Salazar,
  • Alberto Gallardo,
  • Antonio López-Pousa,
  • Raúl Terés,
  • Silvia Bagué,
  • Ruth Orellana,
  • Caterina Fumagalli,
  • Ramon Mangues and
  • Ana Sebio
  • + 3 authors

Poor long-term survival in localized high-risk soft tissue sarcomas (STSs) of the extremities and trunk highlights the need to identify new prognostic factors. CXCR4 is a chemokine receptor involved in tumor progression, angiogenesis, and metastasis....

  • Article
  • Open Access
8 Citations
5,744 Views
15 Pages

Sodium–Glucose Cotransporter 2 Inhibitor Combined with Conventional Diuretics Ameliorate Body Fluid Retention without Excessive Plasma Volume Reduction

  • Maki Asakura-Kinoshita,
  • Takahiro Masuda,
  • Kentaro Oka,
  • Ken Ohara,
  • Marina Miura,
  • Masato Morinari,
  • Kyohei Misawa,
  • Yasuharu Miyazawa,
  • Tetsu Akimoto and
  • Daisuke Nagata
  • + 1 author

We previously reported that sodium–glucose cotransporter 2 (SGLT2) inhibitors exert sustained fluid homeostatic actions through compensatory increases in osmotic diuresis-induced vasopressin secretion and fluid intake. However, SGLT2 inhibitors...

  • Communication
  • Open Access
1 Citations
2,804 Views
12 Pages

Development of a Colorimetric Loop-Mediated Isothermal Amplification Assay for the Detection of Trypanosoma cruzi in Low-Resource Settings

  • Taylor J. Moehling,
  • Myla D. Worthington,
  • Pui-Yan G. Wong,
  • Season S. Wong and
  • Robert J. Meagher

Chagas disease is an inflammatory parasitic infection caused by Trypanosoma cruzi (T. cruzi). Early diagnosis is crucial in guiding treatment and slowing disease progression; however, current diagnostic methods have insufficient detection limits and...

  • Article
  • Open Access
12 Citations
2,981 Views
8 Pages

The present study aimed to explore the clinical applicability of ultrasound super-resolution imaging (US SRI) for assessing renal microcirculation in patients with acute kidney injury (AKI). A total of 62 patients with sepsis were enrolled in the pre...

  • Article
  • Open Access
4 Citations
2,064 Views
15 Pages

Glaucoma is a chronic eye condition that seriously impairs vision and requires early diagnosis and treatment. Automated detection techniques are essential for obtaining a timely diagnosis. In this paper, we propose a novel method for feature selectio...

  • Article
  • Open Access
7 Citations
2,590 Views
10 Pages

Characterization and Antimicrobial Susceptibility Patterns of Enterococcus Species Isolated from Nosocomial Infections in a Saudi Tertiary Care Hospital over a Ten-Year Period (2012–2021)

  • Ali Al Bshabshe,
  • Abdullah Algarni,
  • Yahya Shabi,
  • Abdulrahman Alwahhabi,
  • Mohammed Asiri,
  • Ahmed Alasmari,
  • Adil Alshehry,
  • Wesam F. Mousa and
  • Nashwa Noreldin

Introduction: The Enterococcus genus is a common cause of nosocomial infections, with vancomycin-resistant enterococci (VRE) posing a significant treatment challenge. Method: This retrospective study, spanning ten years (2012 to 2021), analyzes antim...

  • Review
  • Open Access
9 Citations
7,272 Views
17 Pages

A Comprehensive Review on Alcohol Abuse Disorder Fatality, from Alcohol Binges to Alcoholic Cardiomyopathy

  • Antonina Argo,
  • Walter Pitingaro,
  • Maria Puntarello,
  • Roberto Buscemi,
  • Ginevra Malta,
  • Tommaso D’Anna,
  • Giuseppe Davide Albano and
  • Stefania Zerbo

Frequent and excessive consumption of alcohol, be it episodic or sustained misuse, ranks among the top causes of mortality globally. This comprehensive analysis seeks to elucidate how alcohol misuse precipitates death, with a particular focus on asso...

  • Article
  • Open Access
3 Citations
3,924 Views
13 Pages

Post-Treatment Occurrence of Serum Cryoglobulinemia in Chronic Hepatitis C Patients

  • Gantogtokh Dashjamts,
  • Amin-Erdene Ganzorig,
  • Yumchinsuren Tsedendorj,
  • Ganchimeg Dondov,
  • Otgongerel Nergui,
  • Tegshjargal Badamjav,
  • Chung-Feng Huang,
  • Po-Cheng Liang,
  • Tulgaa Lonjid and
  • Chia-Yen Dai
  • + 1 author

Background: Persistent cryoglobulinemia after the completion of antiviral treatment is an important consideration of clinical management in chronic hepatitis C patients. We aimed to investigate the occurrence of serum cryoglobulinemia in chronic hepa...

  • Review
  • Open Access
15 Citations
17,901 Views
13 Pages

Systemic lupus erythematosus (SLE) is a chronic autoimmune condition that can seriously impair multiple organs including the nervous system, causing neuropsychiatric SLE (NPSLE), which encompasses a broad range of symptoms. Pathogenesis is not comple...

  • Case Report
  • Open Access
1 Citations
2,053 Views
12 Pages

Endovascular Stenting for Idiopathic Stenosis of the Superior Mesenteric Vein: A Case Report

  • Mugur Cristian Grasu,
  • Radu Lucian Dumitru,
  • Gina-Ionela Rusu-Munteanu,
  • Mariana Mihaila,
  • Mircea Manuc and
  • Ioana Gabriela Lupescu

Idiopathic superior mesenteric vein (SMV) stenosis, where no clear causative factor is identifiable, remains a clinical rarity. We present a detailed case report of a patient with idiopathic stenosis of the SMV who underwent successful endovascular s...

  • Article
  • Open Access
2,981 Views
17 Pages

Live-Birth Incidence of Isolated D-Transposition of Great Arteries—The Shift in Trends Due to Early Diagnosis

  • Andreea Florentina Stancioi-Cismaru,
  • Marina Dinu,
  • Andreea Carp-Veliscu,
  • Razvan Grigoras Capitanescu,
  • Razvan Cosmin Pana,
  • Ovidiu Costinel Sirbu,
  • Florentina Tanase,
  • Florentina Gratiela Dita,
  • Maria Adelina Popa and
  • Stefania Tudorache
  • + 2 authors

This is a single tertiary population-based study conducted at a center in southwest Romania. We retrospectively compared data obtained in two periods: January 2008–December 2013 and January 2018–December 2023. The global incidence of the...

  • Article
  • Open Access
3 Citations
2,085 Views
9 Pages

Transition from Transrectal to Transperineal MRI-Fusion Prostate Biopsy Does Not Comprise Detection Rates of Clinically Significant Prostate Cancer at a Tertiary Care Center

  • Benedikt Hoeh,
  • Mike Wenzel,
  • Clara Humke,
  • Cristina Cano Garcia,
  • Carolin Siech,
  • Melissa Schneider,
  • Carsten Lange,
  • Miriam Traumann,
  • Jens Köllermann and
  • Philipp Mandel
  • + 2 authors

Background: A remarkable paradigm shift has emerged regarding the preferred prostate biopsy approach, favoring the transperineal (TP) over the transrectal (TR) approach due to the reduced risk of severe urinary tract infections. However, its impact o...

  • Article
  • Open Access
3 Citations
3,628 Views
14 Pages

Evaluation of the Performance of an Artificial Intelligence (AI) Algorithm in Detecting Thoracic Pathologies on Chest Radiographs

  • Hubert Bettinger,
  • Gregory Lenczner,
  • Jean Guigui,
  • Luc Rotenberg,
  • Elie Zerbib,
  • Alexandre Attia,
  • Julien Vidal and
  • Pauline Beaumel

The purpose of the study was to assess the performance of readers in diagnosing thoracic anomalies on standard chest radiographs (CXRs) with and without a deep-learning-based AI tool (Rayvolve) and to evaluate the standalone performance of Rayvolve i...

  • Article
  • Open Access
7 Citations
5,097 Views
14 Pages

Predicting Rheumatoid Arthritis Development Using Hand Ultrasound and Machine Learning—A Two-Year Follow-Up Cohort Study

  • Mahyar Daskareh,
  • Azin Vakilpour,
  • Erfan Barzegar-Golmoghani,
  • Saeid Esmaeilian,
  • Samira Gilanchi,
  • Fatemeh Ezzati,
  • Majid Alikhani,
  • Elham Rahmanipour,
  • Niloofar Amini and
  • Parham Pezeshk
  • + 1 author

Background: The early diagnosis and treatment of rheumatoid arthritis (RA) are essential to prevent joint damage and enhance patient outcomes. Diagnosing RA in its early stages is challenging due to the nonspecific and variable clinical signs and sym...

  • Article
  • Open Access
2 Citations
3,911 Views
26 Pages

Advances in Inflammatory Bowel Disease Diagnostics: Machine Learning and Genomic Profiling Reveal Key Biomarkers for Early Detection

  • Asif Hassan Syed,
  • Hamza Ali S. Abujabal,
  • Shakeel Ahmad,
  • Sharaf J. Malebary and
  • Nashwan Alromema

This study, utilizing high-throughput technologies and Machine Learning (ML), has identified gene biomarkers and molecular signatures in Inflammatory Bowel Disease (IBD). We could identify significant upregulated or downregulated genes in IBD patient...

  • Systematic Review
  • Open Access
5 Citations
5,230 Views
16 Pages

Evaluation of Bitemark Analysis’s Potential Application in Forensic Identification: A Systematic Review

  • Nikolaos Christoloukas,
  • Anastasia Mitsea,
  • Aliki Rontogianni,
  • Evangelos Papadakis and
  • Christos Angelopoulos

Bitemark analysis involves the examination of both patterned injuries and contextual circumstances, combining morphological and positional data. Considering the uniqueness of human dentition, bitemarks caused by teeth on skin or impressions on flexib...

  • Systematic Review
  • Open Access
6 Citations
7,449 Views
20 Pages

Diagnosis and Management of Simple and Complicated Meconium Ileus in Cystic Fibrosis, a Systematic Review

  • Mădălina Andreea Donos,
  • Gabriela Ghiga,
  • Laura Mihaela Trandafir,
  • Elena Cojocaru,
  • Viorel Țarcă,
  • Lăcrămioara Ionela Butnariu,
  • Valentin Bernic,
  • Eugenia Moroșan,
  • Iulia Cristina Roca and
  • Elena Țarcă
  • + 1 author

The early management of neonates with meconium ileus (MI) and cystic fibrosis (CF) is highly variable across countries and is not standardized. We conducted a systematic review according to the Preferred Reporting Items for Systematic Reviews and Met...

  • Review
  • Open Access
7 Citations
3,161 Views
13 Pages

Speckle Tracking Echocardiography in Patients with Non-Ischemic Dilated Cardiomyopathy Who Undergo Cardiac Resynchronization Therapy: A Narrative Review

  • Nikolaos Antoniou,
  • Maria Kalaitzoglou,
  • Lamprini Tsigkriki,
  • Amalia Baroutidou,
  • Adam Tsaousidis,
  • George Koulaouzidis,
  • George Giannakoulas and
  • Dafni Charisopoulou

Non-ischemic dilated cardiomyopathy (DCM) represents a significant cause of heart failure, defined as the presence of left ventricular (LV) dilatation and systolic dysfunction unexplained solely by abnormal loading conditions or coronary artery disea...

  • Article
  • Open Access
1 Citations
1,713 Views
13 Pages

Measurement of Scapholunate Joint Space Width on Real-Time MRI—A Feasibility Study

  • Jonathan Ehmig,
  • Kijanosh Lehmann,
  • Günther Engel,
  • Fabian Kück,
  • Joachim Lotz,
  • Sebastian Aeffner,
  • Ali Seif Amir Hosseini,
  • Arndt F. Schilling and
  • Babak Panahi

Introduction: The scapholunate interosseous ligament is pivotal for wrist stability, and its impairment can result in instability and joint degeneration. This study explores the application of real-time MRI for dynamic assessment of the scapholunate...

  • Article
  • Open Access
1 Citations
1,766 Views
13 Pages

Patient-Reported Outcome Measures in Patients with and without Non-Expandable Lung Secondary to Malignant Pleural Effusion—A Single-Centre Observational Study

  • Jesper Koefod Petersen,
  • Katrine Fjaellegaard,
  • Daniel Bech Rasmussen,
  • Gitte Alstrup,
  • Asbjørn Høegholm,
  • Jatinder Sing Sidhu,
  • Rahul Bhatnagar,
  • Paul Frost Clementsen,
  • Christian B. Laursen and
  • Uffe Bodtger

Background: Malignant pleural effusion (MPE) affects up to 15% of patients with malignancy, and the prevalence is increasing. Non-expandable lung (NEL) complicates MPE in up to 30% of cases. However, it is not known if patients with malignant pleural...

  • Systematic Review
  • Open Access
3 Citations
2,377 Views
10 Pages

Targeted axillary dissection (TAD), employing marked lymph node biopsy (MLNB) alongside sentinel lymph node biopsy (SLNB), is increasingly recognised for its efficacy in reducing false negative rates (FNRs) in node-positive early breast cancer patien...

  • Article
  • Open Access
6 Citations
2,823 Views
19 Pages

Tuberculosis (TB) is an infectious disease caused by Mycobacterium. It primarily impacts the lungs but can also endanger other organs, such as the renal system, spine, and brain. When an infected individual sneezes, coughs, or speaks, the virus can s...

  • Article
  • Open Access
2 Citations
1,328 Views
10 Pages

Right Bundle Branch Block Predicts Appropriate Implantable Cardioverter Defibrillator Therapies in Patients with Non-Ischemic Dilated Cardiomyopathy and a Prophylactic Implantable Cardioverter Defibrillator

  • Marta Jiménez-Blanco Bravo,
  • Gonzalo Luis Alonso Salinas,
  • Carolina Parra Esteban,
  • Jorge Toquero Ramos,
  • Miguel Amores Luque,
  • Jose Luis Zamorano Gómez,
  • Eusebio García-Izquierdo,
  • Jesús Álvarez-García,
  • Ignacio Fernández Lozano and
  • Víctor Castro Urda

Background: The benefit of prophylactic implantable cardioverter defibrillators (ICDs) in patients with severe systolic dysfunction of non-ischemic origin is still unclear, and the identification of patients at risk for sudden cardiac death remains a...

  • Review
  • Open Access
3 Citations
2,642 Views
14 Pages

Struma Ovarii during Pregnancy

  • Gabriela Dumachița-Șargu,
  • Răzvan Socolov,
  • Teodora Ana Balan,
  • Dumitru Gafițanu,
  • Mona Akad and
  • Raluca Anca Balan

Struma ovarii is a rare type of ovarian teratoma primarily composed of over 50% thyroid tissue. Its occurrence is reported in 2–5% of all ovarian teratomas, with approximately 0.5% to 10% showing malignant transformation. Managing it during pre...

  • Article
  • Open Access
4 Citations
1,908 Views
21 Pages

Orthodontic System Modeled and Simulated with the Lingual Technique to Assess Tooth Forces

  • Abbas Hazem,
  • Felicia Ileana Mărășescu,
  • Mihaela Jana Țuculină,
  • Alexandru Dan Popescu,
  • Dragoș Laurențiu Popa,
  • Lelia Laurența Mihai,
  • Cristian Niky Cumpătă,
  • Alexandru Iliescu,
  • Petre Mărășescu and
  • Ionela Teodora Dascălu

CBCT (cone beam computed tomography) is an imaging investigation that provides three-dimensional (3D) images of craniofacial structures. The purpose of this study is to determine the mechanical behavior of an orthodontic system where the lingual trea...

  • Article
  • Open Access
1 Citations
2,156 Views
22 Pages

A Magnetic Resonance Spectroscopy Study on Polarity Subphenotypes in Bipolar Disorder

  • Georgios D. Argyropoulos,
  • Foteini Christidi,
  • Efstratios Karavasilis,
  • Peter Bede,
  • Georgios Velonakis,
  • Anastasia Antoniou,
  • Ioannis Seimenis,
  • Nikolaos Kelekis,
  • Nikolaos Smyrnis and
  • Panagiotis Ferentinos
  • + 2 authors

Although magnetic resonance spectroscopy (MRS) has provided in vivo measurements of brain chemical profiles in bipolar disorder (BD), there are no data on clinically and therapeutically important onset polarity (OP) and predominant polarity (PP). We...

  • Review
  • Open Access
3 Citations
3,137 Views
21 Pages

Neurosurgical Intervention for Nerve and Muscle Biopsies

  • Ali A. Mohamed,
  • Thomas Caussat,
  • Edwin Mouhawasse,
  • Rifa Ali,
  • Phillip M. Johansen and
  • Brandon Lucke-Wold

(1) Background: Neurologic and musculoskeletal diseases represent a considerable portion of the underlying etiologies responsible for the widely prevalent symptoms of pain, weakness, numbness, and paresthesia. Because of the subjective and often nons...

  • Article
  • Open Access
16 Citations
2,588 Views
22 Pages

Can Artificial Intelligence “Hold” a Dermoscope?—The Evaluation of an Artificial Intelligence Chatbot to Translate the Dermoscopic Language

  • Emmanouil Karampinis,
  • Olga Toli,
  • Konstantina-Eirini Georgopoulou,
  • Elli Kampra,
  • Christina Spyridonidou,
  • Angeliki-Victoria Roussaki Schulze and
  • Efterpi Zafiriou

This survey represents the first endeavor to assess the clarity of the dermoscopic language by a chatbot, unveiling insights into the interplay between dermatologists and AI systems within the complexity of the dermoscopic language. Given the complex...

  • Review
  • Open Access
9 Citations
3,208 Views
17 Pages

A Comprehensive Review of the Global Epidemiology, Clinical Management, Socio-Economic Impacts, and National Responses to Long COVID with Future Research Directions

  • Xiufang Song,
  • Weiwei Song,
  • Lizhen Cui,
  • Tim Q. Duong,
  • Rajiv Pandy,
  • Hongdou Liu,
  • Qun Zhou,
  • Jiayao Sun,
  • Yanli Liu and
  • Tong Li

Background: Long COVID, characterized by a persistent symptom spectrum following SARS-CoV-2 infection, poses significant health, social, and economic challenges. This review aims to consolidate knowledge on its epidemiology, clinical features, and un...

  • Article
  • Open Access
1,616 Views
11 Pages

The aim of this study is to investigate whether there is a cut-off value for PD-L1 expression in large B-cell lymphomas that predicts prognosis, and to clarify the relationship between PD-L1 expression and histopathological as well as clinical parame...

  • Article
  • Open Access
1,964 Views
14 Pages

Clinical and Analytical Comparison of Monoclonal and Polyclonal Immunoassays for Fecal Pancreatic Elastase

  • Jasna Lenicek Krleza,
  • Merica Aralica,
  • Lara Milevoj Kopcinovic and
  • Renata Zrinski Topic

Background: Numerous immunoassays have been commercialized to determine pancreatic elastase (PE) in feces in screening for exocrine pancreatic insufficiency (EPI), but how the different assays compare to one another is controversial, especially in th...

  • Article
  • Open Access
1,414 Views
10 Pages

Private Doctors’ Perspective towards “Patient First” in TB Diagnostic Cascade, Hisar, India

  • Sanjeev Saini,
  • Banuru Muralidhara Prasad,
  • Ajay Mahajan,
  • Akshay Duhan,
  • Anuj Jangra,
  • Jitendra Gauttam,
  • Mandeep Malik,
  • Jyoti Kayesth,
  • Bhavin Vadera and
  • Reeti Desai Hobson

TB diagnosis has been simplified in India following advances in available diagnostic tools. This facilitates private doctors’ “patient first” approach toward early diagnosis; however, costs remain high. India’s NTEP establishe...

  • Article
  • Open Access
1 Citations
1,796 Views
13 Pages

Human papillomavirus (HPV) infection has emerged as an etiologic factor of squamous papilloma (SP). The oropharynx and larynx are common sites of SP, but studies on the prevalence of HPV infection in these sites are lacking. This study aimed to evalu...

  • Article
  • Open Access
2 Citations
2,786 Views
13 Pages

The Pterygomandibular Space: A Volumetric Evaluation Using the Novel A-Silicone Injections Method

  • Hadi Darawsheh,
  • Ali Alsaegh,
  • Elena Kanukoeva,
  • Rinat Saleev,
  • Gulshat Saleeva,
  • Beatrice Volel,
  • Natalia Kireeva,
  • Ekaterina Rebrova and
  • Yuriy L. Vasil’ev

Inferior alveolar nerve block (IANB) is one of the most common procedures in operative dentistry, and a deep understanding of the normal anatomical variation of the pterygomandibular space (PM) is essential for its safe and successful administration....

  • Interesting Images
  • Open Access
1,939 Views
2 Pages

Ectopic “Ectopic” Gastric Mucosa

  • Adeel Haq and
  • Amin Haghighat Jahromi

Meckel’s diverticulum is a developmental GI anomaly. It is a remnant of the omphalomesenteric duct (vitelline duct) and the most common congenital anomaly found in the small intestine. It contains ectopic/heterotopic gastric mucosa in half of t...

  • Article
  • Open Access
1,370 Views
12 Pages

FOT Technique Applied for Monitoring of COVID-19 Pneumonia Reveals Small Airways Involvement

  • Immanuels Taivans,
  • Laura Grima,
  • Normunds Jurka,
  • Ligita Zvaigzne,
  • Valentina Gordjušina and
  • Gunta Strazda

The fact that some SARS-CoV-2 pneumonia patients benefit from changing body position, and some from continuous positive airways pressure (CPAP), indicates the functional character of hypoxia. We hypothesize that such effects could be explained by the...

  • Article
  • Open Access
2 Citations
2,681 Views
11 Pages

Venous Thromboembolism Prophylaxis in Gynecologic Oncology: A MITO-MaNGO Survey

  • Michele Mongelli,
  • Domenica Lorusso,
  • Vanna Zanagnolo,
  • Sandro Pignata,
  • Nicoletta Colombo and
  • Gennaro Cormio

Cancer-associated thrombosis is the second leading cause of death in cancer patients, and its incidence has been increasing in recent years. This survey was aimed at gathering information regarding the management of thromboembolic prophylaxis within...

  • Article
  • Open Access
6 Citations
2,050 Views
17 Pages

Development and Validation of an Ultrasonography-Based Machine Learning Model for Predicting Outcomes of Bruxism Treatments

  • Kaan Orhan,
  • Gokhan Yazici,
  • Merve Önder,
  • Cengiz Evli,
  • Melek Volkan-Yazici,
  • Mehmet Eray Kolsuz,
  • Nilsun Bağış,
  • Nihan Kafa and
  • Fehmi Gönüldaş

Background and Objectives: We aimed to develop a predictive model for the outcome of bruxism treatments using ultrasonography (USG)-based machine learning (ML) techniques. This study is a quantitative research study (predictive modeling study) in whi...

  • Article
  • Open Access
2 Citations
1,875 Views
10 Pages

Frozen Section of Placental Membranes and Umbilical Cord: A Valid Diagnostic Tool for Early-Onset Neonatal Sepsis Management

  • Veronica Parrella,
  • Michele Paudice,
  • Michela Pittaluga,
  • Alessandra Allodi,
  • Ezio Fulcheri,
  • Francesca Buffelli,
  • Fabio Barra,
  • Simone Ferrero,
  • Cesare Arioni and
  • Valerio Gaetano Vellone

Early-onset neonatal sepsis (EONS), a serious infection in newborns within 3 days, is challenging to diagnose. The current methods often lack accuracy, leading to unnecessary antibiotics or delayed treatment. This study investigates the role of the f...

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Diagnostics - ISSN 2075-4418