Advancing Open Science

Efforts to reduce food waste in restaurants are crucial for business efficiency, environmental sustainability, and social responsibility. Food waste varies by restaurant type, operations, menu offerings, and customer behavior, yet research on effective reduction strategies remains limited, particularly in Greece and Armenia. This study aims to identify key approaches to minimizing food waste in these countries. Using fuzzy-set Qualitative Comparative Analysis (fsQCA), a method for examining complex causal relationships, we analyzed multiple cases to determine conditions that lead to reduced food waste. Four main paths emerged: (1) digital inventory management combined with educational programs, excluding customer choice enhancement; (2) digital inventory management with flexible dining options, without customer choice enhancement; (3) educational programs with flexible dining, excluding customer choice enhancement; and (4) the combination of digital inventory management, educational programs, and flexible dining. Most cases demonstrating these paths were observed in Greece, indicating more advanced food waste management practices. Interviews highlighted recurring themes such as overordering, portion control, supplier challenges, and the importance of education and policy grounded in social responsibility. The findings provide actionable insights for restaurants and policymakers seeking effective strategies to reduce food waste and promote sustainable practices.

Several fruit fly species in the Drosophilidae and Tephritidae families are classified as invasive pests worldwide. However, limited information is available on the occurrence of those dipteran species, their interactions, and their host plants in the Pampa Biome of southern Brazil. Therefore, we investigated interactions between invasive fruit flies and host plants. After two years (2022–2023) of fruit surveys, 3802 fruits from 16 plant species were harvested in the Pampa Biome’s urban and rural areas. The collected fruits were conditioned in the laboratory. Emerged adult flies were identified and associated with the respective fruit species. The most abundant species detected were Zaprionus indianus (Gupta), followed by Zaprionus tuberculatus (Malloch), Drosophila suzukii (Matsumura), and Ceratitis capitata (Wiedemann). The invasive drosophilids D. suzukii, Z. indianus and Z. tuberculatus interacted with 10 host plant species each, whereas C. capitata was associated with seven host species. Zaprionus indianus showed the highest infestation rate on fruits collected from the ground, whereas D. suzukii had the highest infestation rate in fruits attached to plants. New host plants were identified for Z. tuberculatus and C. capitata. The findings of this study provide a valuable framework for more effective management and control strategies.

Human serum albumin (HSA) is one of the main proteins in human blood plasma and serves as a molecular “taxi” transporting various compounds, including organic compounds, drugs, metal ions, etc., through the circulatory system throughout the human body. As with any other proteins, HSA hydration plays an important role in maintaining its structure and functioning as well as influencing its ability to bind to ligands. This contribution presents, for the first time, a generalized picture of hydration of this biomacromolecule obtained within the framework of the 3D-RISM (three-dimensional Reference Interaction Site Model) theory of solvation. Based on 3D isodensity maps and structural parameters (hydration numbers, hydration layer thickness, fraction of hydrogen bonds, SASA, etc.), the most probable model of HSA hydration structure was reconstructed. With the description of HSA hydration, two important issues were also addressed in detail. The first is the correct determination of the hydration layer thickness, a common problem in protein science. The second is the possible state and behavior of hydration water in HSA–ligand binding. The presented results provide a deeper understanding of the relationship between solvent and HSA, which brings new knowledge to the understanding of protein hydration.

Advanced two-dimensional (2D) beam steering is essential for unlocking the full potential of terahertz (THz) systems in future 6G communications and high-resolution imaging. However, achieving wide-angle, high-speed, and high-precision 2D beam control within a compact THz platform remains a significant challenge. In this work, we experimentally demonstrate an optoelectronic $2\times 2$ THz antenna array that enables flexible 2D beam steering, beam hopping, and beam scanning around the 300 GHz band. This work employs a $2\times 2$ microstrip patch antenna (MPA) array directly driven by InGaAs/InP UTC-PDs on a silicon carbide (SiC) substrate. The relative phases of the four radiating elements are precisely programmed using an optical phased array (OPA), which provides fully decoupled and low-latency phase control in the optical domain. Experimentally, we demonstrate 2D beam steering and 2D beam hopping among three representative directions at a polar angle of ${25}^{\circ }$ and azimuth angles of ${60}^{\circ }$, ${180}^{\circ }$, and ${300}^{\circ }$. Furthermore, continuous 2D beam scanning at a fixed polar angle of ${25}^{\circ }$ is achieved, enabling a full ${360}^{\circ }$ azimuth sweep within 0.43 s while maintaining high beam quality. These results confirm that the proposed UTC-PD based $2\times 2$ MPA array provides a practical and robust approach for 2D THz beam manipulation, and offers strong potential for future 6G wireless links and THz imaging applications.

The pitting corrosion resistance and the tribological behaviour of a ferritic stainless steel with high Mo content (AISI 436) and a commonly employed austenitic stainless steel (AISI 304) are compared. Special attention was paid to the role of Mo in improving corrosion resistance of ferritic stainless steels. Since the surface condition is an important parameter related to the onset of pitting corrosion in the presence of chlorides, three different surface finishes were tested for both steels. Two commercial finishing grades and laboratory polishing down to 1 µm were compared. Moreover, the influence of surface condition on the tribological properties for both steels was also evaluated. The study demonstrates that surface finishing plays a decisive role in both the electrochemical and mechanical response of stainless steels. A comprehensive microstructural and tribological analysis reveals not only how commercial finishing treatments modify passive film behaviour, but also how they affect friction stability and wear mechanisms. Special emphasis is placed on the synergistic effect between molybdenum content, passive film integrity and manufacturing processes. The obtained results provide valuable insight for industrial applications where durability against chloride exposure and abrasion is critical.

The angle of repose is a fundamental parameter for assessing the stability of coral reefs. However, predictive models for this angle are currently lacking. In this study, a series of laboratory experiments were undertaken to investigate the angle of repose by varying moisture content, particle shape, and particle size. Based on our experimental data, variation in the angle of repose with moisture content is classified into five distinct zones. It is demonstrated that the range of moisture content for each zone varies with particle size. Coral sands of dendrite, flake, rod, and block particles have a descending order of angle of repose, as demonstrated for a sieve size of 4.5 mm. The angle of repose for dry, submerged, and steady coral sands exhibits a correlation with the nominal diameter of particle size. Finally, extended models are proposed for predicting the angle of repose of coral sands (R² = 0.8, D_n50 = 0.317−5.470). To facilitate use of these models, a linear relationship between sieve particle size diameter, nominal particle size diameter, and Corey shape factor, allowing for conversion among these parameters, is established. This study thereby helps to enhance our understanding of how moisture content affects angle of repose and improve our ability to predict the angle for coral grains with intricate geometries.

Background/Objectives: In recent years, it has been suggested that sedatives may cause brain damage. One possible mechanism is interference with oxidative phosphorylation of brain mitochondria, but much remains unknown. In this study, we focused on dexmedetomidine, midazolam, and propofol, essential sedatives in anesthesia and intensive care, and aimed to understand the effects of these drugs on mouse brain mitochondria. Methods: We measured changes in mitochondrial respiratory capacity and swelling rate upon exposure to these sedatives in a wide concentration range. For the sedative that demonstrated impaired mitochondrial function we explored the possible involvement of mitochondrial permeability transition pore opening using brain mitochondria from cyclophilin D knockout (CypD KO) mice and detected cytochrome c (cyt c) release by Western blot. Results: Of the three sedatives, only high concentrations of propofol exhibited reduced respiratory capacity and mitochondrial swelling, toxicity which was not prevented by CypD KO. Furthermore, propofol did not induce cyt c release. Conclusions: These results suggest that propofol-induced brain mitochondrial dysfunction is a mechanism independent of mPTP opening.

Background: Inadequate nutrition, poor health care, and limited stimulation constrain early childhood development and cognitive potential. Micronutrient deficiencies during pregnancy and early life are prevalent in low- and middle-income countries (LMICs) and may impair cognitive outcomes. Maternal multiple-micronutrient (MMN) and point-of-use micronutrient powder (MNP) supplements improve birth outcomes and iron status, but their long-term cognitive impact remains unclear. This systematic review assessed the long-term impact of maternal MMN and early-childhood MNP supplementation on cognitive development among children aged 4–14 years in LMICs. Method: Following PRISMA guidelines (PROSPERO CRD42023459846), (cluster) randomized controlled trials were identified from six databases and gray literature (October 2023; updated July 2025). Records were managed in EndNote and screened in Covidence, and data were synthesized using Review Manager. Eligible studies examined MMN or MNP interventions during pregnancy, lactation, or early childhood, reporting cognitive, motor, or socio-emotional outcomes in children aged 4–14. Results: Ten studies met the inclusion criteria: six on maternal supplementation, three on early childhood interventions, and one combining both. Most were conducted in Asia, with one in Tanzania and one in Peru. Although most findings were not statistically significant, two large UNIMMAP-based trials indicated modest long-term improvements in procedural memory and intelligence, while one early childhood point-of-use MNP trial suggested enhanced pre-academic skills. Conclusions: Maternal MMN supplementation may modestly enhance specific domains of cognitive development, whereas evidence on the long-term effects of MMN and point-of-use MNPs on cognitive development remain limited, highlighting the necessity for further research.